SOX2 Monoclonal Antibody (20G5), DyLight 488 | Invitrogen MA1-014-D488 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOX2 Monoclonal Antibody (20G5), DyLight 488

catalog :

MA1-014-D488

quantity :

100 uL

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

DyLight488

clone name :

20G5

The same clone is also sold as:

Abcam: ab171380

reactivity :

human, mouse

application :

immunocytochemistry

citations: 3

Reference
Marelli E, Hughes J, Scotting P. SUMO-dependent transcriptional repression by Sox2 inhibits the proliferation of neural stem cells. PLoS ONE. 2024;19:e0298818 pubmed publisher
Wu Y, Tay H, Yang J, Liao H, Ma Y, Wei Y. Mitochondrial impairment and synaptic dysfunction are associated with neurological defects in iPSCs-derived cortical neurons of MERRF patients. J Biomed Sci. 2023;30:70 pubmed publisher
Matrone G, Thandavarayan R, Walther B, Meng S, Mojiri A, Cooke J. Dysfunction of iPSC-derived endothelial cells in human Hutchinson-Gilford progeria syndrome. Cell Cycle. 2019;18:2495-2508 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SOX2 Monoclonal Antibody (20G5), DyLight 488

Catalog # :

MA1-014-D488

Quantity :

100 uL

Price :

US 399.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100

Species :

Human, Mouse

Clone :

20G5

Isotype :

IgG1, kappa

Storage :

4 C, do not freeze

Description :

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.

Immunogen :

Full-length human recombinant protein expressed in bacteria

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100

Aliases :

ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389