RAP1A Monoclonal Antibody (1D2-1C64) | Invitrogen MA1-013 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RAP1A Monoclonal Antibody (1D2-1C64)

catalog :

MA1-013

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D2-1C64

The same clone is also sold as:

Novus Biologicals: NBP2-22526
Abcam: ab175329

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Reference
Khan A, Ni W, Baltazar T, Lopez Giraldez F, Pober J, Pierce R. ArhGEF12 activates Rap1A and not RhoA in human dermal microvascular endothelial cells to reduce tumor necrosis factor-induced leak. FASEB J. 2022;36:e22254 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RAP1A Monoclonal Antibody (1D2-1C64)

Catalog # :

MA1-013

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 2 ug, Western Blot: 1:500-1:1,000

Species :

Human, Mouse

Clone :

1D2-1C64

Isotype :

IgG2a

Storage :

-20 C

Description :

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

Immunogen :

Recombinant full-length human Rap1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 2 ug, Western Blot: 1:500-1:1,000

Aliases :

AI848598; C21KG; G-22K; GTP-binding protein; GTP-binding protein smg p21A; GTP-binding protein SMG-P21A; KREV1; Krev-1; rap 1A; RAP1; RAP1A; RAP-1A; RAP1A, member of RAS oncogene family; RAS-related protein 1a; ras-related protein Krev-1; Ras-related protein Rap-1A; RAS-related protein-1a; SMGP21