IL-8 (CXCL8) Monoclonal Antibody (I8-S2), Biotin | Invitrogen M802B product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-8 (CXCL8) Monoclonal Antibody (I8-S2), Biotin

catalog :

M802B

quantity :

250 µg

price :

US 496

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

I8-S2

reactivity :

human, mouse

application :

western blot, ELISA

more info or order :

Invitrogen product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Salem S, Harris T, Mok J, Li M, Keenan C, Schuliga M, et al. Transforming growth factor-? impairs glucocorticoid activity in the A549 lung adenocarcinoma cell line. Br J Pharmacol. 2012;166:2036-48 pubmed publisher
ELISA; human	Tan W, Sabet L, Li Y, Yu T, Klokkevold P, Wong D, et al. Optical protein sensor for detecting cancer markers in saliva. Biosens Bioelectron. 2008;24:266-71 pubmed publisher
ELISA; human	Saffar A, Alphonse M, Shan L, Hayglass K, Simons F, Gounni A. IgE modulates neutrophil survival in asthma: role of mitochondrial pathway. J Immunol. 2007;178:2535-41 pubmed
ELISA; human	Urbanowska T, Mangialaio S, Zickler C, Cheevapruk S, Hasler P, Regenass S, et al. Protein microarray platform for the multiplex analysis of biomarkers in human sera. J Immunol Methods. 2006;316:1-7 pubmed
ELISA; mouse ELISA; human	Jenmalm M, Cherwinski H, Bowman E, Phillips J, Sedgwick J. Regulation of myeloid cell function through the CD200 receptor. J Immunol. 2006;176:191-9 pubmed
	Seiser S, Cerbu D, Gallhofer A, Matiasek J, Elbe B xfc rger A. Comparative assessment of commercially available wound gels in ex vivo human skin reveals major differences in immune response-modulatory effects. Sci Rep. 2022;12:17481 pubmed publisher
	Jalili P, Krause B, Lanceleur R, Burel A, Jungnickel H, Lampen A, et al. Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines. Part Fibre Toxicol. 2022;19:37 pubmed publisher
	Kantrong N, Chang A, Bamashmous S, Hajjar A, BUCALA R, Darveau R. Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells. J Periodontol. 2022;93:1940-1950 pubmed publisher
	Seiser S, Janker L, Zila N, Mildner M, Rakita A, Matiasek J, et al. Octenidine-based hydrogel shows anti-inflammatory and protease-inhibitory capacities in wounded human skin. Sci Rep. 2021;11:32 pubmed publisher
	Chang A, Bamashmous S, Darveau R, Rajapakse S. An Ayurvedic herbal extract inhibits oral epithelial cell IL-8 responses to host and bacterial agonists. BMC Complement Med Ther. 2020;20:62 pubmed publisher
	Alarcan J, Barbé S, Kopp B, Hessel Pras S, Braeuning A, Lampen A, et al. Combined effects of okadaic acid and pectenotoxin-2, 13-desmethylspirolide C or yessotoxin in human intestinal Caco-2 cells. Chemosphere. 2019;228:139-148 pubmed publisher
	Ming H, Tian A, Liu B, Hu Y, Liu C, Chen R, et al. Inflammatory cytokines tumor necrosis factor-α, interleukin-8 and sleep monitoring in patients with obstructive sleep apnea syndrome. Exp Ther Med. 2019;17:1766-1770 pubmed publisher
	Croasdell A, Sime P, Phipps R. Resolvin D2 decreases TLR4 expression to mediate resolution in human monocytes. FASEB J. 2016;30:3181-93 pubmed publisher
	Sahler J, Woeller C, Phipps R. Microparticles engineered to highly express peroxisome proliferator-activated receptor-Î³ decreased inflammatory mediator production and increased adhesion of recipient monocytes. PLoS ONE. 2014;9:e113189 pubmed publisher
	Moore H, Ivey R, Voytovich U, Lin C, Stirewalt D, Pogosova Agadjanyan E, et al. The human salivary proteome is radiation responsive. Radiat Res. 2014;181:521-30 pubmed publisher
	McMillan D, Woeller C, Thatcher T, Spinelli S, Maggirwar S, Sime P, et al. Attenuation of inflammatory mediator production by the NF-?B member RelB is mediated by microRNA-146a in lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2013;304:L774-81 pubmed publisher
	Beigi R, Kertesy S, Aquilina G, Dubyak G. Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor-independent mechanisms. Br J Pharmacol. 2003;140:507-19 pubmed
	Urbanowska T, Mangialaio S, Hartmann C, Legay F. Development of protein microarray technology to monitor biomarkers of rheumatoid arthritis disease. Cell Biol Toxicol. 2003;19:189-202 pubmed
	Meloni F, Cascina A, Paschetto E, Marone Bianco A, Morosini M, Pellegrini C, et al. Monocyte chemoattractant protein-1 levels in bronchoalveolar lavage fluid of lung-transplanted patients treated with tacrolimus as rescue treatment for refractory acute rejection. Transplant Proc. 2003;35:1523-6 pubmed
	Singh R, Varney M. Regulation of interleukin 8 expression in human malignant melanoma cells. Cancer Res. 1998;58:1532-7 pubmed

product information

Product Type :

Antibody

Product Name :

IL-8 (CXCL8) Monoclonal Antibody (I8-S2), Biotin

Catalog # :

M802B

Quantity :

250 µg

Price :

US 496

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

I8-S2

Isotype :

IgG2b, kappa

Storage :

-20°C

Description :

Interleukin 8 (IL-8, CXCL8) is a 72 amino acid pro-inflammatory factor which belongs to the CXC subfamily of chemokines, and are bound by the cell surface receptors IL-8RA and IL-8RB. IL-8 functions as a chemoattractant and potent angiogenic factor. The expression and secretion of IL-8 can be induced by diverse inflammatory stimuli in many cells, including macrophages and endothelial cells. In endothelial cells, IL-8 is present in storage vesicles called Weibel-Palade bodies. IL-8, first isolated from osteosarcoma cells, contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors. Previous nomenclature for IL-8 includes neutrophil activating protein 1 (NAP-1), granulocyte chemotactic protein 1 (GCP-1), monocyte-derived neutrophil-activating peptide (MONAP) and protein 3-10C. IL-8 and ten other members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. Cancer studies have demonstrated a role for IL-8 in the angiogenesis and growth of tumours, and IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection.

Immunogen :

Recombinant human IL-8

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Aliases :

(Ala-IL-8)77; (Ser-IL-8)72; Alveolar macrophage chemotactic factor I; alveolar macrophage-derived chemotactic factor-I; AMCF-I; ANX7; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine 8; C-X-C motif chemokine ligand 8; CXCL8; cytokine 8; emoctakin; GCP/IL-8 protein I; GCP/IL-8 protein II; GCP/IL-8 protein III; GCP/IL-8 protein IV; GCP/IL-8 protein V; GCP/IL-8 protein VI; GCP1; GCP-1; Granulocyte chemotactic protein 1; IL8; IL-8; IL-8(1-77); IL-8(5-77); IL-8(6-77); IL-8(7-77); IL-8(8-77); IL-8(9-77); IL8/NAP1 form I; IL8/NAP1 form II; IL8/NAP1 form III; IL8/NAP1 form IV; IL8/NAP1 form V; IL8/NAP1 form VI; ILN; Interleukin; interleukin 8; Interleukin8; interleukin-8; interleuklin-8 precursor; LECT; LUCT; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; Lymphocyte-derived neutrophil-activating factor; LYNAP; MDNCF; MDNCF-a; MDNCF-b; MDNCF-c; MONAP; Monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; NAF; NAP1; NAP-1; neutrophil activating peptide 1; neutrophil and T-lymphocyte chemotactic and activating factor; Neutrophil attractant/activation protein 1; neutrophil attractant/activation protein-1; Neutrophil-activating factor; neutrophil-activating peptide 1; Neutrophil-activating protein 1; Permeability factor 1; PF1; Protein 3-10C; RP11-537A6.8; RPF1; small inducible cytokine subfamily B, member 8; SNX; SYNEXIN; T-cell chemotactic factor; tumor necrosis factor-induced gene 1

more info or order :

Invitrogen product webpage