IFN alpha Monoclonal Antibody (7N41), Biotin | Invitrogen M710B product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IFN alpha Monoclonal Antibody (7N41), Biotin

catalog :

M710B

quantity :

250 µg

price :

US 466

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

7N41

reactivity :

human

application :

western blot, ELISA

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
ELISA; human western blot; human; 1:400	Ayed A, Rabhi I, Dellagi K, Kallel H. High level production and purification of human interferon ?2b in high cell density culture of Pichia pastoris. Enzyme Microb Technol. 2008;42:173-80 pubmed publisher
ELISA; human	Noble J, Wang L, Cerasoli E, Knight A, Porter R, Gray E, et al. An international comparability study to determine the sources of uncertainty associated with a non-competitive sandwich fluorescent ELISA. Clin Chem Lab Med. 2008;46:1033-45 pubmed publisher
	Li Q, Ding X, Thomas J, Harding C, Pecora N, Ziady A, et al. Rv2468c, a novel Mycobacterium tuberculosis protein that costimulates human CD4+ T cells through VLA-5. J Leukoc Biol. 2012;91:311-20 pubmed publisher
	Gurney K, Colantonio A, Blom B, Spits H, Uittenbogaart C. Endogenous IFN-alpha production by plasmacytoid dendritic cells exerts an antiviral effect on thymic HIV-1 infection. J Immunol. 2004;173:7269-76 pubmed
	Bolt G, Berg K, Blixenkrone Møller M. Measles virus-induced modulation of host-cell gene expression. J Gen Virol. 2002;83:1157-65 pubmed
	Egilmez N, Jong Y, Hess S, Jacob J, Mathiowitz E, Bankert R. Cytokines delivered by biodegradable microspheres promote effective suppression of human tumors by human peripheral blood lymphocytes in the SCID-Winn model. J Immunother. 2000;23:190-5 pubmed
	Herr W, Schneider J, Lohse A, Meyer zum Buschenfelde K, Wolfel T. Detection and quantification of blood-derived CD8+ T lymphocytes secreting tumor necrosis factor alpha in response to HLA-A2.1-binding melanoma and viral peptide antigens. J Immunol Methods. 1996;191:131-42 pubmed

product information

Product Type :

Antibody

Product Name :

IFN alpha Monoclonal Antibody (7N41), Biotin

Catalog # :

M710B

Quantity :

250 µg

Price :

US 466

Clonality :

Monoclonal

Purity :

Caprylic acid precipitation

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent

Species :

Human

Clone :

7N41

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.

Immunogen :

Recombinant human IFN alpha 2b

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

alpha-2a interferon; Gm12597; ifa; Ifa1; Ifa2; IFL; IFN; IFN alpha; IFN alpha 1/13; IFN alpha 1b; IFN a; IFN1@; IFNA; IFNA@; IFNA1; IFNA13; Ifna15; Ifna2; IFNA2A; IFNA2B; IFNA2C; IFNA3; IFNA6; Ifnaa; IFNAalphaIFN-alpha-1/13; IFNalpha; IFN-alpha; IFN-alpha 1b; IFN-alpha1; IFN-alpha-1; IFN-alpha-1/13; IFN-alpha-2; IFN-alpha-6; IFN-alphaA; IFN-alphaD; IFN-gamma; IFNa; INFA2; interferon; interferon alpha; interferon alpha 1; Interferon alpha 13 (IFNA13); interferon alpha 15; interferon alpha 1b; interferon alpha 2; interferon alpha 2a; interferon alpha 2b; interferon alpha A; interferon alpha family gene 1; interferon alpha family, gene 2; Interferon alpha leukocyte (IFL); interferon alpha protein; interferon alpha-1; Interferon alpha1 (IFNA1); interferon alpha-1 precursor; interferon alpha-1/13; Interferon alpha-1/13 (IFN-alpha-1/13); Interferon alpha-2; Interferon alpha-A; Interferon alpha-D; Interferon alpha-D (IFN alphaD); interferon type A1/A2; interferon type A3; interferon, alpha 1; interferon, alpha 2; interferon-alpha; interferon-alpha 1; interferon-alpha1; interferon-alpha-6; leIF A; LeIF D; MGC138207; MGC138505; MGC138507; MuIFN-alpha-A; novel interferon alpha (Ifna) family member; OTTMUSG00000007655

more info or order :

Invitrogen product webpage