IL-2 Monoclonal Antibody (B-G5), Biotin | Invitrogen M600B product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-2 Monoclonal Antibody (B-G5), Biotin

catalog :

M600B

quantity :

250 µg

price :

US 514

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

B-G5

reactivity :

human

application :

western blot, ELISA

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Alonso Camino V, Sánchez Martín D, Compte M, Nuñez Prado N, Diaz R, Vile R, et al. CARbodies: Human Antibodies Against Cell Surface Tumor Antigens Selected From Repertoires Displayed on T Cell Chimeric Antigen Receptors. Mol Ther Nucleic Acids. 2013;2:e93 pubmed publisher
ELISA; human	Alonso Camino V, Sánchez Martín D, Compte M, Sanz L, Alvarez Vallina L. Lymphocyte display: a novel antibody selection platform based on T cell activation. PLoS ONE. 2009;4:e7174 pubmed publisher
western blot; human	Shi C, Yuan S, Zhang H, Zhang T, Wang L, Xu Z. Cell-mediated immune responses and protective efficacy against infection with Mycobacterium tuberculosis induced by Hsp65 and hIL-2 fusion protein in mice. Scand J Immunol. 2009;69:140-9 pubmed publisher
ELISA; human	Loewenbrueck K, Tigno Aranjuez J, Boehm B, Lehmann P, Tary Lehmann M. Th1 responses to beta-amyloid in young humans convert to regulatory IL-10 responses in Down syndrome and Alzheimer's disease. Neurobiol Aging. 2010;31:1732-42 pubmed publisher
ELISA; human	Shindo T, Ishikawa T, Fukunaga A, Hori T, Uchiyama T. Growth and differentiation advantages of CD4+ OX40+ T cells from allogeneic hematopoietic stem cell transplantation recipients. Biol Blood Marrow Transplant. 2008;14:268-81 pubmed publisher
ELISA; human	Nowacki T, Kuerten S, Zhang W, Shive C, Kreher C, Boehm B, et al. Granzyme B production distinguishes recently activated CD8(+) memory cells from resting memory cells. Cell Immunol. 2007;247:36-48 pubmed
ELISA; human	Kuekrek H, Schlingmann T, Valdez H, Boehm B, Pollard R, Mitsuyasu R, et al. Differential effect of interleukin-2 treatment on primary and secondary immunizations in HIV infected individuals. AIDS. 2005;19:1967-74 pubmed
ELISA; human; 0.125 ug/ml	Quast S, Zhang W, Shive C, Kovalovski D, Ott P, Herzog B, et al. IL-2 absorption affects IFN-gamma and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays. Cell Immunol. 2005;237:28-36 pubmed
	Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med. 2017;214:1129-1151 pubmed publisher
	Guerkov R, Targoni O, Kreher C, Boehm B, Herrera M, Tary Lehmann M, et al. Detection of low-frequency antigen-specific IL-10-producing CD4(+) T cells via ELISPOT in PBMC: cognate vs. nonspecific production of the cytokine. J Immunol Methods. 2003;279:111-21 pubmed
	Kreher C, Dittrich M, Guerkov R, Boehm B, Tary Lehmann M. CD4+ and CD8+ cells in cryopreserved human PBMC maintain full functionality in cytokine ELISPOT assays. J Immunol Methods. 2003;278:79-93 pubmed
	Valdez H, Anthony D, Farukhi F, Patki A, Salkowitz J, Heeger P, et al. Immune responses to hepatitis C and non-hepatitis C antigens in hepatitis C virus infected and HIV-1 coinfected patients. AIDS. 2000;14:2239-46 pubmed
	Hartig C, Haller G, Sachs D, Kuhlenschmidt S, Heeger P. Naturally developing memory T cell xenoreactivity to swine antigens in human peripheral blood lymphocytes. J Immunol. 2000;164:2790-6 pubmed
	Heeger P, Greenspan N, Kuhlenschmidt S, Dejelo C, Hricik D, Schulak J, et al. Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol. 1999;163:2267-75 pubmed

product information

Product Type :

Antibody

Product Name :

IL-2 Monoclonal Antibody (B-G5), Biotin

Catalog # :

M600B

Quantity :

250 µg

Price :

US 514

Clonality :

Monoclonal

Purity :

Ion-exchange chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

B-G5

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Immunogen :

Recombinant human IL-2

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Aliases :

aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF

more info or order :

Invitrogen product webpage