GM-CSF Monoclonal Antibody (1089), Biotin | Invitrogen M501B product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GM-CSF Monoclonal Antibody (1089), Biotin

catalog :

M501B

quantity :

250 µg

price :

US 410

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

1089

reactivity :

human

application :

ELISA

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Yakimchuk K, Roura Mir C, Magalhaes K, de Jong A, Kasmar A, Granter S, et al. Borrelia burgdorferi infection regulates CD1 expression in human cells and tissues via IL1-?. Eur J Immunol. 2011;41:694-705 pubmed publisher
	Cakouros D, Cockerill P, Bert A, Mital R, Roberts D, Shannon M. A NF-kappa B/Sp1 region is essential for chromatin remodeling and correct transcription of a human granulocyte-macrophage colony-stimulating factor transgene. J Immunol. 2001;167:302-10 pubmed
	Kanakura Y, Cannistra S, Brown C, Nakamura M, Seelig G, Prosise W, et al. Identification of functionally distinct domains of human granulocyte-macrophage colony-stimulating factor using monoclonal antibodies. Blood. 1991;77:1033-43 pubmed

product information

Product Type :

Antibody

Product Name :

GM-CSF Monoclonal Antibody (1089), Biotin

Catalog # :

M501B

Quantity :

250 µg

Price :

US 410

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent

Species :

Human

Clone :

1089

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

Immunogen :

Glycosylated, CHO-derived recombinant human GM-CSF

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim

more info or order :

Invitrogen product webpage