GM-CSF Monoclonal Antibody (1089) | Invitrogen M501 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GM-CSF Monoclonal Antibody (1089)

catalog :

M501

quantity :

500 µg

price :

US 410

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1089

reactivity :

human

application :

ELISA

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Burke S, Issekutz T, Mohan K, Lee P, Shmulevitz M, Marshall J. Human mast cell activation with virus-associated stimuli leads to the selective chemotaxis of natural killer cells by a CXCL8-dependent mechanism. Blood. 2008;111:5467-76 pubmed publisher
	Tsunoda M, Litonjua A, Kuniak M, Weiss S, Satoh T, Guevarra L, et al. Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy Immunol. 2003;130:158-64 pubmed
	Kim M, Manoukian R, Yeh R, Silbiger S, Danilenko D, Scully S, et al. Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. Blood. 2002;100:2330-40 pubmed
	Gao W, Wortis H, Pereira M. The Trypanosoma cruzi trans-sialidase is a T cell-independent B cell mitogen and an inducer of non-specific Ig secretion. Int Immunol. 2002;14:299-308 pubmed
	Lee C, Kim J, Kim K, Han S. A mouse thymic stromal cell line producing macrophage-colony stimulating factor and interleukin-6. Arch Pharm Res. 2000;23:252-6 pubmed
	Lees C, Apostolopoulos V, Acres B, Ong C, Popovski V, McKenzie I. The effect of T1 and T2 cytokines on the cytotoxic T cell response to mannan-MUC1. Cancer Immunol Immunother. 2000;48:644-52 pubmed
	Cavallo F, Signorelli P, Giovarelli M, Musiani P, Modesti A, Brunda M, et al. Antitumor efficacy of adenocarcinoma cells engineered to produce interleukin 12 (IL-12) or other cytokines compared with exogenous IL-12. J Natl Cancer Inst. 1997;89:1049-58 pubmed
	Rennert P, Furlong K, Jellis C, Greenfield E, Freeman G, Ueda Y, et al. The IgV domain of human B7-2 (CD86) is sufficient to co-stimulate T lymphocytes and induce cytokine secretion. Int Immunol. 1997;9:805-13 pubmed
	Vitkovic L, Chatham J, da Cunha A. Distinct expressions of three cytokines by IL-1-stimulated astrocytes in vitro and in AIDS brain. Brain Behav Immun. 1995;9:378-88 pubmed
	Gabriele L, Kaido T, Woodrow D, Moss J, Ferrantini M, Proletti E, et al. Local and systemic response of mice to interferon-alpha 1-transfected Friend leukemia cells. Am J Pathol. 1995;147:445-60 pubmed
	Kanakura Y, Cannistra S, Brown C, Nakamura M, Seelig G, Prosise W, et al. Identification of functionally distinct domains of human granulocyte-macrophage colony-stimulating factor using monoclonal antibodies. Blood. 1991;77:1033-43 pubmed

product information

Product Type :

Antibody

Product Name :

GM-CSF Monoclonal Antibody (1089)

Catalog # :

M501

Quantity :

500 µg

Price :

US 410

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent

Species :

Human

Clone :

1089

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

Immunogen :

Glycosylated, CHO-derived recombinant human GM-CSF

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim

more info or order :

Invitrogen product webpage