IL-4 Monoclonal Antibody (E10023) | Invitrogen M3IL4I product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-4 Monoclonal Antibody (E10023)

catalog :

M3IL4I

quantity :

500 µg

price :

US 446

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

E10023

reactivity :

human

application :

western blot, ELISA

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
ELISA; human; 1.5 ug/ml; fig 6b	Mufarrege E, Giorgetti S, Etcheverrigaray M, Terry F, Martin W, De Groot A. De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy. Clin Immunol. 2017;176:31-41 pubmed publisher
	Li S, Ma X, Xie J, Yan X, Sun W. MicroRNA-206, IL-4, IL-13, and INF-γ levels in lung tissue and plasma are increased by the stimulation of particulate matter with a diameter of ≤2.5μm, and are associated with the poor prognosis of asthma induced pulmonary arterial. Clin Exp Hypertens. 2021;43:181-188 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL-4 Monoclonal Antibody (E10023)

Catalog # :

M3IL4I

Quantity :

500 µg

Price :

US 446

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 0.005-20 µg/mL, Western Blot: 1:1,000

Species :

Human

Clone :

E10023

Isotype :

IgG2a

Storage :

4° C

Description :

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

Immunogen :

Recombinant human IL-4 purified from Pichia pastoris

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.005-20 µg/mL, Western Blot: 1:1,000

Aliases :

B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

more info or order :

Invitrogen product webpage