IL-13 Monoclonal Antibody (5A2), Biotin | Invitrogen M130B product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-13 Monoclonal Antibody (5A2), Biotin

catalog :

M130B

quantity :

250 µg

price :

US 514

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

5A2

reactivity :

human

application :

western blot, ELISA

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Lozano E, Joller N, Cao Y, Kuchroo V, Hafler D. The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans. J Immunol. 2013;191:3673-80 pubmed publisher
ELISA; human	Hainaut M, Verscheure V, Ducarme M, Schandene L, Levy J, Mascart F. Cellular immune responses in human immunodeficiency virus (HIV)-1-infected children: is immune restoration by highly active anti-retroviral therapy comparable to non-progression?. Clin Exp Immunol. 2011;165:77-84 pubmed publisher
ELISA; human	Kato Kogoe N, Ohyama H, Nishimura F, Meguro M, Yoshizawa S, Okada Y, et al. Fibroblasts stimulated via HLA-II molecules produce prostaglandin E? and regulate cytokine production from helper T cells. Lab Invest. 2010;90:1747-56 pubmed publisher
ELISA; human	Malhotra I, Dent A, Mungai P, Wamachi A, Ouma J, Narum D, et al. Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya. PLoS Med. 2009;6:e1000116 pubmed publisher
ELISA; human	Marotti B, Rocco A, De Colibus P, Compare D, de Nucci G, Staibano S, et al. Interleukin-13 mucosal production in Helicobacter pylori-related gastric diseases. Dig Liver Dis. 2008;40:240-7 pubmed publisher
ELISA; human	Mascart F, Hainaut M, Peltier A, Verscheure V, Levy J, Locht C. Modulation of the infant immune responses by the first pertussis vaccine administrations. Vaccine. 2007;25:391-8 pubmed
ELISA; human	Malhotra I, Mungai P, Muchiri E, Ouma J, Sharma S, Kazura J, et al. Distinct Th1- and Th2-Type prenatal cytokine responses to Plasmodium falciparum erythrocyte invasion ligands. Infect Immun. 2005;73:3462-70 pubmed
	Mascart F, Verscheure V, Malfroot A, Hainaut M, Pierard D, Temerman S, et al. Bordetella pertussis infection in 2-month-old infants promotes type 1 T cell responses. J Immunol. 2003;170:1504-9 pubmed
	Hancock G, Scheuer C, Sierzega R, Pryharski K, McBride J, Watelet L, et al. Adaptive immune responses of patients with asthma to the attachment (G) glycoprotein of respiratory synctial virus. J Infect Dis. 2001;184:1589-93 pubmed

product information

Product Type :

Antibody

Product Name :

IL-13 Monoclonal Antibody (5A2), Biotin

Catalog # :

M130B

Quantity :

250 µg

Price :

US 514

Clonality :

Monoclonal

Purity :

protein A

Host :

Rat

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

5A2

Isotype :

IgG

Storage :

-20°C

Description :

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

Immunogen :

Recombinant human IL-14

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Aliases :

ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600

more info or order :

Invitrogen product webpage