This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SOD2 Polyclonal Antibody
catalog :
LF-PA0021
quantity :
100µL
price :
US 380.00
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000
Ross C, Alston M, Bickenbach J, Aykin Burns N. Oxygen tension changes the rate of migration of human skin keratinocytes in an age-related manner. Exp Dermatol. 2011;20:58-63 pubmed publisher
  • western blot; rat; 1:1,000
Chen X, Choi I, Chang T, Noh Y, Shin C, Wu C, et al. Pretreatment with interferon-gamma protects microglia from oxidative stress via up-regulation of Mn-SOD. Free Radic Biol Med. 2009;46:1204-10 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SOD2 Polyclonal Antibody
Catalog # :
LF-PA0021
Quantity :
100µL
Price :
US 380.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunoprecipitation: 1 µL, Western Blot: 1:2000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Immunogen :
Recombinant human protein purified from E.coli.
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: 1 µL, Western Blot: 1:2000
Aliases :
SOD2, IPO B, Manganese SOD, Manganese superoxide dismutase
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA