TRBP Monoclonal Antibody (46D1) | Invitrogen LF-MA0209 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRBP Monoclonal Antibody (46D1)

catalog :

LF-MA0209

quantity :

100 µL

price :

US 395.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

46D1

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, western blot knockout validation

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:1000; fig 1b	Ding J, Chen J, Wang Y, Kataoka M, Ma L, Zhou P, et al. Trbp regulates heart function through microRNA-mediated Sox6 repression. Nat Genet. 2015;47:776-83 pubmed publisher
western blot; mouse; loading ...; fig 2a	Amen A, Ruiz Garzon C, Shi J, Subramanian M, Pham D, Meffert M. A Rapid Induction Mechanism for Lin28a in Trophic Responses. Mol Cell. 2017;65:490-503.e7 pubmed publisher
western blot; mouse; fig 1	Ding J, Nie M, Liu J, Hu X, Ma L, Deng Z, et al. Trbp Is Required for Differentiation of Myoblasts and Normal Regeneration of Skeletal Muscle. PLoS ONE. 2016;11:e0155349 pubmed publisher
	Wang M, Huang H, Kuo Y, Lo C, Sun H, Lyu Y, et al. TARBP2-Enhanced Resistance during Tamoxifen Treatment in Breast Cancer. Cancers (Basel). 2019;11: pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRBP Monoclonal Antibody (46D1)

Catalog # :

LF-MA0209

Quantity :

100 µL

Price :

US 395.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Western Blot: 0.5 µg/mL

Species :

Human, Mouse

Clone :

46D1

Isotype :

IgG1, kappa

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.

Immunogen :

Recombinant human protein purified from E.coli(GST-TRBP)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Western Blot: 0.5 µg/mL

Aliases :

fj51e12; HAMAP-Rule:MF_03034}; LOQS; Prbp; PRM-1 RNA-binding protein; protamine-1 RNA-binding protein; RISC-loading complex subunit tarbp2; RISC-loading complex subunit TARBP2 {ECO:0000255; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; TAR (HIV-1) RNA binding protein 2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TARBP2; TARBP2 subunit of RISC loading complex; TARBP2, RISC loading complex RNA binding subunit; trans-activation responsive RNA-binding protein; trans-activation-responsive RNA-binding protein; TRBP; TRBP1; TRBP2; wu:fj51e12; zgc:63778