Kallikrein 6 Monoclonal Antibody (9A7) | Invitrogen LF-MA0153 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Kallikrein 6 Monoclonal Antibody (9A7)

catalog :

LF-MA0153

quantity :

100 µL

price :

US 395.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9A7

reactivity :

human

application :

western blot, immunocytochemistry

citations: 15

Reference
Fleet J, Eksir F, Hance K, Wood R. Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines. Am J Physiol Gastrointest Liver Physiol. 2002;283:G618-25 pubmed
Thompson P, Jurutka P, Haussler C, Whitfield G, Haussler M. Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis-retinoic acid. Evidence for allosteric receptor interactions. J Biol Chem. 1998;273:8483-91 pubmed
Barsony J, Renyi I, McKoy W. Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand. J Biol Chem. 1997;272:5774-82 pubmed
Mackey S, Heymont J, Kronenberg H, Demay M. Vitamin D receptor binding to the negative human parathyroid hormone vitamin D response element does not require the retinoid x receptor. Mol Endocrinol. 1996;10:298-305 pubmed
Liu S, Koszewski N, Lupez M, Malluche H, Olivera A, Russell J. Characterization of a response element in the 5'-flanking region of the avian (chicken) PTH gene that mediates negative regulation of gene transcription by 1,25-dihydroxyvitamin D3 and binds the vitamin D3 receptor. Mol Endocrinol. 1996;10:206-15 pubmed
Ch ng J, Ibrahim B. Transcriptional and posttranscriptional mechanisms modulate creatine kinase expression during differentiation of osteoblastic cells. J Biol Chem. 1994;269:2336-41 pubmed
Ferrari S, Battini R, Molinari S. Specific binding to vitamin D response elements of chicken intestinal DNA-binding activity is not related to the vitamin D receptor. Mol Endocrinol. 1994;8:173-81 pubmed
Lasky S, Posner M, Iwata K, Santos Moore A, Yen A, Samuel V, et al. Characterization of a vitamin D3-resistant human chronic myelogenous leukemia cell line. Blood. 1994;84:4283-94 pubmed
Pike J, Donaldson C, Marion S, Haussler M. Development of hybridomas secreting monoclonal antibodies to the chicken intestinal 1 alpha,25-dihydroxyvitamin D3 receptor. Proc Natl Acad Sci U S A. 1982;79:7719-23 pubmed
Pike J, Marion S, Donaldson C, Haussler M. Serum and monoclonal antibodies against the chick intestinal receptor for 1,25-dihydroxyvitamin D3. Generation by a preparation enriched in a 64,000-dalton protein. J Biol Chem. 1983;258:1289-96 pubmed
Pike J. Monoclonal antibodies to chick intestinal receptors for 1,25-dihydroxyvitamin D3. Interaction and effects of binding on receptor function. J Biol Chem. 1984;259:1167-73 pubmed
Milde P, Merke J, Ritz E, Haussler M, Rauterberg E. Immunohistochemical detection of 1,25-dihydroxyvitamin D3 receptors and estrogen receptors by monoclonal antibodies: comparison of four immunoperoxidase methods. J Histochem Cytochem. 1989;37:1609-17 pubmed
Mangelsdorf D, Pike J, Haussler M. Avian and mammalian receptors for 1,25-dihydroxyvitamin D3: in vitro translation to characterize size and hormone-dependent regulation. Proc Natl Acad Sci U S A. 1987;84:354-8 pubmed
Hsieh J, Jurutka P, Galligan M, Terpening C, Haussler C, Samuels D, et al. Human vitamin D receptor is selectively phosphorylated by protein kinase C on serine 51, a residue crucial to its trans-activation function. Proc Natl Acad Sci U S A. 1991;88:9315-9 pubmed
MacDonald P, Haussler C, Terpening C, Galligan M, Reeder M, Whitfield G, et al. Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor. J Biol Chem. 1991;266:18808-13 pubmed

product information

Product Type :

Antibody

Product Name :

Kallikrein 6 Monoclonal Antibody (9A7)

Catalog # :

LF-MA0153

Quantity :

100 µL

Price :

US 395.00

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:250, Western Blot: 1:1,000

Species :

Human

Clone :

9A7

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.

Immunogen :

Recombinant human protein purified from E.coli

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Western Blot: 1:1,000

Aliases :

0610007D04Rik; AI849898; brain serine protease; BSP; Bssp; Glandular kallikrein K1; hK6; Kal; KAL-B; kallikrein 1; kallikrein 29; kallikrein 6; kallikrein 6 (neurosin); kallikrein 6 (neurosin, zyme); kallikrein 7; kallikrein related peptidase 6; kallikrein related-peptidase 6; kallikrein renal/pancreas/salivary; kallikrein-1; Kallikrein6; Kallikrein-6; Klk1; Klk1b6; Klk29; Klk6; Klk-6; Klk7; MGC9355; mGK-6; MSP; myelencephalon-specific protease; myofibril-bound protease; neurosin; Protease M; protease serine 9 (neurosin); protease, serine, 18; protease, serine, 9; PRSS18; PRSS9; renal kallikrein; Serine protease 18; serine protease 9; SP59; tissue kallikrein-6; true tissue kallikrein; zyme