PRDX2 Monoclonal Antibody (1E8) | Invitrogen LF-MA0144 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PRDX2 Monoclonal Antibody (1E8)

catalog :

LF-MA0144

quantity :

100 µL

price :

US 425.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1E8

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; loading ...; fig 5c	Yeung P, Lai A, Son H, Zhang X, Hwang O, Chung S, et al. Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson's disease. Neurobiol Aging. 2017;50:119-133 pubmed publisher
	Talwar D, Messens J, Dick T. A role for annexin A2 in scaffolding the peroxiredoxin 2-STAT3 redox relay complex. Nat Commun. 2020;11:4512 pubmed publisher
	Wang S, Chen Z, Zhu S, Lu H, Peng D, Soutto M, et al. PRDX2 protects against oxidative stress induced by H. pylori and promotes resistance to cisplatin in gastric cancer. Redox Biol. 2020;28:101319 pubmed publisher
	Kim M, Lee H, Lee S, Lee H, Huh J, Bae Y, et al. Peroxiredoxin 5 Inhibits Glutamate-Induced Neuronal Cell Death through the Regulation of Calcineurin-Dependent Mitochondrial Dynamics in HT22 Cells. Mol Cell Biol. 2019;39: pubmed publisher
	Liu S, Mahairaki V, Bai H, Ding Z, Li J, Witwer K, et al. Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells. Stem Cells. 2019;37:779-790 pubmed publisher
	Lee E, Lee H. Peroxidase expression is decreased by palmitate in cultured podocytes but increased in podocytes of advanced diabetic nephropathy. J Cell Physiol. 2018;233:9060-9069 pubmed publisher
	Kim J, Park S, Kim B, Choe Y, Lee D. Insulin-stimulated lipid accumulation is inhibited by ROS-scavenging chemicals, but not by the Drp1 inhibitor Mdivi-1. PLoS ONE. 2017;12:e0185764 pubmed publisher
	Hintsala H, Soini Y, Haapasaari K, Karihtala P. Dysregulation of redox-state-regulating enzymes in melanocytic skin tumours and the surrounding microenvironment. Histopathology. 2015;67:348-57 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PRDX2 Monoclonal Antibody (1E8)

Catalog # :

LF-MA0144

Quantity :

100 µL

Price :

US 425.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 µg/mL

Species :

Human, Mouse, Rat

Clone :

1E8

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Immunogen :

Recombinant human protein purified from E.coli

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 µg/mL

Aliases :

AL022839; Band-8; Calpromotin; epididymis secretory sperm binding protein Li 2a; HEL-S-2a; HGNC:9353; MGC4104; Natural killer cell-enhancing factor B; NkefB; NKEF-B; peroxiredoxin 2; peroxiredoxin-2; Prdx2; protector protein; PRP; Prx II-1; PRX2; PRXII; PTX1; Tdpx1; TDX1; thiol specific antioxidant protein; thiol-specific antioxidant 1; thiol-specific antioxidant protein; thioredoxin dependent peroxide reductase 1; thioredoxin peroxidase 1; thioredoxin reductase; thioredoxin-dependent peroxide reductase 1; Torin; TPx; TPX1; TPx-B; TR; Trx dependent peroxide reductase 1; TSA