This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PON1 Monoclonal Antibody (17A12)
catalog :
LF-MA0099
quantity :
100 µL
price :
US 436
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
17A12
reactivity :
human, mouse, rat
application :
western blot
product information
Product Type :
Antibody
Product Name :
PON1 Monoclonal Antibody (17A12)
Catalog # :
LF-MA0099
Quantity :
100 µL
Price :
US 436
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Western Blot: 2-5 µg/mL
Species :
Human, Mouse, Rat
Clone :
17A12
Isotype :
IgG1
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.
Immunogen :
Purified, His-tagged, recombinant, human PON1 protein expressed in E. coli.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 2-5 µg/mL
Aliases :
A esterase 1; A-esterase 1; aromatic esterase 1; arylesterase 1; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESA; ESAesterase A; esterase A; K-45; MVCD5; paraoxonase 1; paraoxonase B-type; Pon; PON 1; PON1; serum aryldiakylphosphatase; serum aryldialkylphosphatase 1; Serum paraoxonase/arylesterase 1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA