PRDX6 Monoclonal Antibody (4A3) | Invitrogen LF-MA0018 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PRDX6 Monoclonal Antibody (4A3)

catalog :

LF-MA0018

quantity :

100 µL

price :

US 446.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4A3

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 2a	Daverey A, Agrawal S. Curcumin alleviates oxidative stress and mitochondrial dysfunction in astrocytes. Neuroscience. 2016;333:92-103 pubmed publisher
	Kim M, Lee H, Lee S, Lee H, Huh J, Bae Y, et al. Peroxiredoxin 5 Inhibits Glutamate-Induced Neuronal Cell Death through the Regulation of Calcineurin-Dependent Mitochondrial Dynamics in HT22 Cells. Mol Cell Biol. 2019;39: pubmed publisher
	Chhunchha B, Singh P, Singh D, Kubo E. Ginkgolic Acid Rescues Lens Epithelial Cells from Injury Caused by Redox Regulated-Aberrant Sumoylation Signaling by Reviving Prdx6 and Sp1 Expression and Activities. Int J Mol Sci. 2018;19: pubmed publisher

product information

Product Type :

Antibody

Product Name :

PRDX6 Monoclonal Antibody (4A3)

Catalog # :

LF-MA0018

Quantity :

100 µL

Price :

US 446.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 0.5 µg/mL, Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 2 µg/mL, Immunoprecipitation: 2 µg, Western Blot: 0.1-1 µg/mL

Species :

Human, Mouse, Rat

Clone :

4A3

Isotype :

IgG2b

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Immunogen :

Purified, recombinant, human peroxiredoxin 6 protein expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.5 µg/mL, Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 2 µg/mL, Immunoprecipitation: 2 µg, Western Blot: 0.1-1 µg/mL

Aliases :

1-Cys; 1-Cys peroxiredoxin; 1-Cys PRX; 1-cysPrx; 24 kDa protein; 9430088D19Rik; AA690119; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; Aop2; Brp-12; CP-3; epididymis secretory sperm binding protein Li 128m; GPx; HEL-S-128m; KIAA0106; Liver 2D page spot 40; Ltw4; Ltw-4; Lvtw-4; MGC46173; MSP23; NKEFA; Non-selenium glutathione peroxidase; NSGPx; ORF06; p29; PAG; PAGA; PAGB; peroxiredoxin 6; peroxiredoxin-6; Prdx5; Prdx6; PRX; Prx6; Red blood cells page spot 12; thiol-specific antioxidant protein; Tsa