This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
ELISA/assay
product name :
Human Amyloid beta 42 ELISA Kit
catalog :
KHB3441
quantity :
96 Tests
price :
844 USD
citations: 26
Reference
Qiao W, Chen Y, Zhong J, Madden B, Charlesworth C, Martens Y, et al. Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology. Mol Neurodegener. 2023;18:8 pubmed publisher
Zhang H, Knight C, Chen S, Bezprozvanny I. A Gating Mutation in Ryanodine Receptor Type 2 Rescues Phenotypes of Alzheimer's Disease Mouse Models by Upregulating Neuronal Autophagy. J Neurosci. 2023;43:1441-1454 pubmed publisher
Simon M, Wang M, Ismail O, Braun M, Schindler A, Reemmer J, et al. Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice. Alzheimers Res Ther. 2022;14:59 pubmed publisher
Ortiz Sanz C, Balantzategi U, Quintela López T, Ruiz A, Luchena C, Zuazo Ibarra J, et al. Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease. Cell Death Dis. 2022;13:253 pubmed publisher
Koh H, Lee S, Lee H, Min J, Iwatsubo T, Teunissen C, et al. Targeting MicroRNA-485-3p Blocks Alzheimer's Disease Progression. Int J Mol Sci. 2021;22: pubmed publisher
Pohlkamp T, Xian X, Wong C, Durakoglugil M, Werthmann G, Saido T, et al. NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load. elife. 2021;10: pubmed publisher
Zhao J, Lu W, Ren Y, Fu Y, Martens Y, Shue F, et al. Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids. Acta Neuropathol. 2021;142:807-825 pubmed publisher
Jeong A, Cheng S, Zhong R, Bennett D, Bergo M, Li L. Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice. Acta Neuropathol Commun. 2021;9:129 pubmed publisher
Shandilya S, Kesari K, Ruokolainen J. Vitamin K2 Modulates Organelle Damage and Tauopathy Induced by Streptozotocin and Menadione in SH-SY5Y Cells. Antioxidants (Basel). 2021;10: pubmed publisher
Li Y, Zhu K, Li N, Wang X, Xiao X, Li L, et al. Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model. Alzheimers Res Ther. 2021;13:114 pubmed publisher
Ruiz Riquelme A, Mao A, Barghash M, Lau H, Stuart E, Kovacs G, et al. Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice. Acta Neuropathol Commun. 2021;9:83 pubmed publisher
Chen G, Kang S, Wang Z, Ahn E, Xia Y, Liu X, et al. Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies. Sci Adv. 2021;7: pubmed publisher
Gauba E, Sui S, Tian J, Driskill C, Jia K, Yu C, et al. Modulation of OSCP mitigates mitochondrial and synaptic deficits in a mouse model of Alzheimer's pathology. Neurobiol Aging. 2021;98:63-77 pubmed publisher
Lackie R, Marques Lopes J, Ostapchenko V, Good S, Choy W, van Oosten Hawle P, et al. Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2020;8:143 pubmed publisher
Evans C, Miners J, Piva G, Willis C, Heard D, Kidd E, et al. ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease. Acta Neuropathol. 2020;139:485-502 pubmed publisher
Meng S, Wang B, Li W. Intermittent hypoxia improves cognition and reduces anxiety-related behavior in APP/PS1 mice. Brain Behav. 2020;10:e01513 pubmed publisher
Gerber H, Mosser S, Boury Jamot B, Stumpe M, Piersigilli A, Goepfert C, et al. The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease. Acta Neuropathol Commun. 2019;7:13 pubmed publisher
Meyer K, Feldman H, Lu T, Drake D, Lim E, Ling K, et al. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Rep. 2019;26:1112-1127.e9 pubmed publisher
McCanney G, McGrath M, Otto T, Burchmore R, Yates E, Bavington C, et al. Low sulfated heparins target multiple proteins for central nervous system repair. Glia. 2019;67:668-687 pubmed publisher
Thygesen C, Ilkjær L, Kempf S, Hemdrup A, von Linstow C, Babcock A, et al. Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1ΔE9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease. Front Cell Neurosci. 2018;12:397 pubmed publisher
Ovchinnikov D, Korn O, Virshup I, Wells C, Wolvetang E. The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome iPSC-Derived Neurons. Stem Cell Reports. 2018;11:32-42 pubmed publisher
Adalbert R, Milde S, Durrant C, Ando K, Stygelbout V, Yilmaz Z, et al. Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport. Neurobiol Aging. 2018;68:68-75 pubmed publisher
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product information
Product Type :
ELISA
Catalog Number :
KHB3441
Category :
ELISA Kits
Target :
Amyloid beta 42
Product Name :
Human Amyloid beta 42 ELISA Kit
Description :
Beta amyloid is a 40–43 amino acid peptide cleaved from amyloid precursor protein by a protease, gamma-secretase. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.
Synonyms :
A beta 1 42; A ß 1 42; A4; AAA; AB42; Abeta; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; Amyloid beta 1 42; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid ß; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; Aß 1 42; B APP42; BAPP42; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; BetaAPP42; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; Cvap; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2; ß APP42; ßAPP42
Price (USD) :
844 USD
Size :
96 Tests
Species Reactivity :
Human
Applications :
ELISA
Storage :
2-8 C
Detection Range :
15.6-1000 pg/mL
Sample Type :
Cerebrospinal Fluid, 50 µL Supernatant, 50 µL Tissue Homogenate, 50 µL
Assay Length :
1 hr 20 min
Note :
This product is for research use only.
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA