KLRG1 Monoclonal Antibody (2F1), FITC | Invitrogen HMKLRG101 product information

product summary

company name :

Invitrogen

other brands :

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product type :

antibody

product name :

KLRG1 Monoclonal Antibody (2F1), FITC

catalog :

HMKLRG101

quantity :

500 ug

price :

US 680.00

clonality :

monoclonal

host :

Syrian golden hamster

conjugate :

FITC

clone name :

2F1

reactivity :

human, mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; loading ...; fig 2a	Splitt S, Souza S, Valentine K, Castellanos B, Curd A, Hoyer K, et al. PD-L1, TIM-3, and CTLA-4 Blockade Fails To Promote Resistance to Secondary Infection with Virulent Strains of Toxoplasma gondii. Infect Immun. 2018;86: pubmed publisher
flow cytometry; mouse; loading ...; fig 10c	Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, et al. Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion. J Exp Med. 2016;213:1881-900 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KLRG1 Monoclonal Antibody (2F1), FITC

Catalog # :

HMKLRG101

Quantity :

500 ug

Price :

US 680.00

Clonality :

Monoclonal

Purity :

purified

Host :

Syrian Hamster

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1 ug/1x10^6 cells

Species :

Human, Mouse

Clone :

2F1

Isotype :

IgG2

Storage :

4 C, store in dark

Description :

KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

Immunogen :

Activated NK (A-LAK) cells from B6 (H-2b) mice.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/1x10^6 cells

Aliases :

2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

more info or order :

Invitrogen product webpage