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ELISA/assay

Human Dnmt3b ELISA Kit

EH158RB

96 Tests

634 USD

EH158RB

ELISA Kits

DNMT3B

Human Dnmt3b ELISA Kit

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB

634 USD

96 Tests

Human

ELISA

2-8 C

0.64-150 ng/mL

Plasma, 50 µL Serum, 50 µL Supernatant, 50 µL

1 hr 20 min

This product is for research use only.