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ELISA/assay

Mouse Complement C5b-9 (soluble) ELISA Kit

EEL207

96 Tests

652 USD

EEL207

ELISA Kits

Complement C5b-9

Mouse Complement C5b-9 (soluble) ELISA Kit

The complement system is a fundamental part of innate immunity, consisting of over 45 genes that encode various complement components, regulators, and receptors. The complement C5b-9 complex, also known as the Membrane Attack Complex (MAC), plays a crucial role in the immune defense mechanism. It includes the sequential assembly of proteins C5b, C6, C7, C8, and multiple copies of C9. This complex forms transmembrane channels that puncture the cell membrane of target cells, leading to cell lysis. Specifically, MAC has significant implications in mediating cell death in both pathogenic organisms and cancer cells. The genes involved are clustered across the human genome, mainly organized in three significant loci. The understanding of the C5b-9 complex's function extends beyond its antimicrobial roles to include its interactions with tumor cells, where it can induce cell death and influence cancer progression.

C5b-9; MAC Complex; Membrane Attack Complex

652 USD

96 Tests

Mouse

ELISA

Refer to product documentation for component specific storage temperature.

0.31-20 ng/mL

Plasma, 100 µL Serum, 100 µL

1 hr 20 min

This product is for research use only.