Complement C5b Monoclonal Antibody (aE11) | Invitrogen DIA 011-01-02 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Complement C5b Monoclonal Antibody (aE11)

catalog :

DIA 011-01-02

quantity :

400 uL

price :

US 1112.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

aE11

The same clone is also sold as:

Abcam: ab237699
Dako: M0777
Santa Cruz Biotechnology: sc-58935

reactivity :

human, pigs , domestic horse

application :

immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 2

Reference
Stødle G, Silva G, Tangerås L, Gierman L, Nervik I, Dahlberg U, et al. Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts. Clin Exp Immunol. 2018;193:84-94 pubmed publisher
Yuen J, Pluthero F, Douda D, Riedl M, Cherry A, Ulanova M, et al. NETosing Neutrophils Activate Complement Both on Their Own NETs and Bacteria via Alternative and Non-alternative Pathways. Front Immunol. 2016;7:137 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Complement C5b Monoclonal Antibody (aE11)

Catalog # :

DIA 011-01-02

Quantity :

400 uL

Price :

US 1112.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Equine, Human, Non-human primate, Porcine

Applications :

ELISA: 1:20,000, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent

Species :

Equine, Human, Non-human primate, Porcine

Clone :

aE11

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark

Description :

C5b-9 is also known as the TCC. TCC consists of C5b, C6, C7, C8 and C9. The complex forms transmembrane channels which displace lipid molecules and other constituents, thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The complex contains neoantigens that are absent from the individual native components and the monoclonal antibody DIA 011-01 is directed against a neoepitope exposed in C9 when incorporated into TCC.

Immunogen :

Purified C5b-9.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:20,000, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent

Aliases :

anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5; C5a; C5a anaphylatoxin; C5b; C5D; CHE1; complement C5; Complement C5 alpha chain; Complement C5 alpha' chain; Complement C5 beta chain; complement C5a anaphylatoxin; complement component 5; complement component C5; CPAMD4; ECLZB; FLJ17816; FLJ17822; MGC142298; prepro-C5