Collagen I Monoclonal Antibody (5D8-G9/Col1) | Invitrogen CSI 008-01-02 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Collagen I Monoclonal Antibody (5D8-G9/Col1)

catalog :

CSI 008-01-02

quantity :

200µl

price :

US 409

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5D8-G9/Col1

reactivity :

domestic goat, human, dogs, bovine, swine, domestic sheep

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 1

Reference
Wang C, Yang K, Lin K, Liu Y, Liu H, Lin F. Cartilage regeneration in SCID mice using a highly organized three-dimensional alginate scaffold. Biomaterials. 2012;33:120-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Collagen I Monoclonal Antibody (5D8-G9/Col1)

Catalog # :

CSI 008-01-02

Quantity :

200µl

Price :

US 409

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Bovine, Canine, Goat, Human, Ovine, Porcine

Applications :

ELISA: 1:16,000, Immunohistochemistry (Frozen): Assay dependent, Immunoprecipitation: Assay dependent, Western Blot: Assay dependent

Species :

Bovine, Canine, Goat, Human, Ovine, Porcine

Clone :

5D8-G9/Col1

Isotype :

IgG1, kappa

Storage :

4° C, store in dark

Description :

Collagen I is a Type I collagen with a triple helix structure comprised of two alpha-1 chains and one alpha-2 chain. Collagen I is a member of group I collagen (fibril-forming collagen) found in most connective tissues, and is abundant in bone, cornea, dermis and tendon. Mutations in the COL1A2 gene encoding the alpha-2 chain are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in the COL1A2 gene which codes for the alpha-2 chain, however, tend to be less severe than mutations in the COL1A1 gene, reflecting the different role of alpha-2 chains in matrix integrity. Reciprocal translocations between chromosomes 17 and 22, where Collagen Type 1 genes and the gene for platelet derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified.

Immunogen :

Pepsin-solublized, salt-fractioned type I collagen from human placenta

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:16,000, Immunohistochemistry (Frozen): Assay dependent, Immunoprecipitation: Assay dependent, Western Blot: Assay dependent

Aliases :

COL1, COL1A2