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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ITGB1 Monoclonal Antibody (MEM-101A), FITC
catalog :
CD2901
quantity :
500 uL
price :
US 354.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
MEM-101A
reactivity :
human, domestic sheep
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • flow cytometry; domestic sheep; 1:10; fig 3
Khan M, Chandrashekran A, Smith R, Dudhia J. Immunophenotypic characterization of ovine mesenchymal stem cells. Cytometry A. 2016;89:443-50 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b
Mvula B, Abrahamse H. Differentiation Potential of Adipose-Derived Stem Cells When Cocultured with Smooth Muscle Cells, and the Role of Low-Intensity Laser Irradiation. Photomed Laser Surg. 2016;34:509-515 pubmed
  • flow cytometry; human
Adesida A, Mulet Sierra A, Jomha N. Hypoxia mediated isolation and expansion enhances the chondrogenic capacity of bone marrow mesenchymal stromal cells. Stem Cell Res Ther. 2012;3:9 pubmed publisher
  • flow cytometry; human; fig 4
Farias V, Linares Fernández J, Peñalver J, Payá Colmenero J, Ferrón G, Duran E, et al. Human umbilical cord stromal stem cell express CD10 and exert contractile properties. Placenta. 2011;32:86-95 pubmed publisher
  • flow cytometry; human; 1:20; tbl 1
Chui K, Trivedi A, Cheng C, Cherbavaz D, Dazin P, Huynh A, et al. Characterization and functionality of proliferative human Sertoli cells. Cell Transplant. 2011;20:619-35 pubmed publisher
Khalkar P, Díaz Argelich N, Antonio Palop J, Sanmartin C, Fernandes A. Novel Methylselenoesters Induce Programed Cell Death via Entosis in Pancreatic Cancer Cells. Int J Mol Sci. 2018;19: pubmed publisher
Weiss W, Mulet Sierra A, Kunze M, Jomha N, Adesida A. Coculture of meniscus cells and mesenchymal stem cells in simulated microgravity. NPJ Microgravity. 2017;3:28 pubmed publisher
Mitchell J, McIntosh K, Zvonic S, Garrett S, Floyd Z, Kloster A, et al. Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers. Stem Cells. 2006;24:376-85 pubmed
product information
Product Type :
Antibody
Product Name :
ITGB1 Monoclonal Antibody (MEM-101A), FITC
Catalog # :
CD2901
Quantity :
500 uL
Price :
US 354.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent
Species :
Human
Clone :
MEM-101A
Isotype :
IgG1
Storage :
4 C, store in dark
Description :
ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins. ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug. ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue. Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease. Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta. More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. The distribution pattern in adult tissues for integrin beta types are mutually exclusive. Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.
Immunogen :
Human CD29
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent
Aliases :
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA