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ELISA/assay

E-selectin (Soluble) Monkey Instant ELISA™ Kit

BMS649INST

128 tests

654.00 USD

BMS649INST

ELISA Kits

E-selectin

E-selectin (Soluble) Monkey Instant ELISA™ Kit

E-selectin (CD62E, ELAM-1, and LECAM-1) is a 115 kD type I membrane protein and a member of the selectin family. E-selectin is highly expressed on activated endothelial cells (IL-2, TNF- alpha, other cytokines can increase expression) and can also be expressed on endothelial cells in the skin, bone marrow and placenta. E-selectin is involved in tethering and leucocyte rolling on activated endothelium at inflammatory sites and may also play a role in tumor metastasis and angiogenesis. E-selectin binds to both Siayl Lewis X (CD15s) and PSGL-1 (CD162). The HCD62E antibody has been shown to recognize human E-selectin and to be useful for flow cytometry. In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.

654.00 USD

128 tests

Baboon

ELISA

-20°C

1.88-60 U/mL

Plasma, 20 µL Serum, 20 µL Supernatant, 20 µL

20 min

This product is for research use only.