Mouse IL-10 Recombinant Protein, eBioscience | Invitrogen BMS347 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Mouse IL-10 Recombinant Protein, eBioscience

catalog :

BMS347

quantity :

10 ug

price :

US 656.00

citations: 1

Reference
Tsitsilashvili E, Sepashvili M, Chikviladze M, Shanshiashvili L, Mikeladze D. Myelin basic protein charge isomers change macrophage polarization. J Inflamm Res. 2019;12:25-33 pubmed publisher

product information

Product Type :

Protein

Product Name :

Mouse IL-10 Recombinant Protein, eBioscience

Catalog # :

BMS347

Quantity :

10 ug

Price :

US 656.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Mouse

Applications :

Control: Assay-Dependent

Species :

Mouse

Storage :

-20 C

Description :

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

Format :

Lyophilized

Applications w/Dilutions :

Control: Assay-Dependent

Aliases :

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF