CD126 Monoclonal Antibody (B-R6), eBioscience | Invitrogen BMS135 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD126 Monoclonal Antibody (B-R6), eBioscience

catalog :

BMS135

quantity :

100 ug

price :

US 257.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B-R6

The same clone is also sold as:

OriGene: AM31357PU-N, AM31357FC-N, AM31357AF-N
Abcam: ab47215, ab27321
Bio-Rad: MCA822

reactivity :

human

application :

flow cytometry

citations: 4

Reference
Zhang W, Yin G, Zhao H, Ling H, Xie Z, Xiao C, et al. Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner. Cell Death Dis. 2021;12:102 pubmed publisher
Soroosh A, Albeiroti S, West G, Willard B, Fiocchi C, De La Motte C. Crohn's Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan Fragments. Cell Mol Gastroenterol Hepatol. 2016;2:358-368.e4 pubmed
Yi H, Kim Y, Kim J, Jung H, Rim Y, Jung S, et al. A new strategy to deliver synthetic protein drugs: self-reproducible biologics using minicircles. Sci Rep. 2014;4:5961 pubmed publisher
McCoy Simandle K, Stewart C, Dao J, DebRoy S, Rossier O, Bryce P, et al. Legionella pneumophila type II secretion dampens the cytokine response of infected macrophages and epithelia. Infect Immun. 2011;79:1984-97 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD126 Monoclonal Antibody (B-R6), eBioscience

Catalog # :

BMS135

Quantity :

100 ug

Price :

US 257.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent

Species :

Human

Clone :

B-R6

Isotype :

IgG1

Storage :

4 C

Description :

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Immunogen :

Rec. Human IL-6R (CD126)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent

Aliases :

CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991