CD50 (ICAM-3) Monoclonal Antibody (CBR-IC3/1), eBioscience | Invitrogen BMS111 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD50 (ICAM-3) Monoclonal Antibody (CBR-IC3/1), eBioscience

catalog :

BMS111

quantity :

50 ug

price :

US 259.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CBR-IC3/1

The same clone is also sold as:

BioLegend: 330016, 330017, 330005, 330018, 330011, 330015, 330002

reactivity :

human

application :

immunohistochemistry, flow cytometry

citations: 1

Reference
Kozuka M, Battaglin F, Jayachandran P, Wang J, Arai H, Soni S, et al. Clinical Significance of Circulating Tumor Cell Induced Epithelial-Mesenchymal Transition in Patients with Metastatic Colorectal Cancer by Single-Cell RNA-Sequencing. Cancers (Basel). 2021;13: pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD50 (ICAM-3) Monoclonal Antibody (CBR-IC3/1), eBioscience

Catalog # :

BMS111

Quantity :

50 ug

Price :

US 259.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent

Species :

Human

Clone :

CBR-IC3/1

Isotype :

IgG1

Storage :

4 C

Description :

CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.

Immunogen :

Rec. Human ICAM-3 (CD50)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent

Aliases :

CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3