CD54 (ICAM-1) Monoclonal Antibody (RR1/1), eBioscience | Invitrogen BMS108 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD54 (ICAM-1) Monoclonal Antibody (RR1/1), eBioscience

catalog :

BMS108

quantity :

50 µg

price :

US 212

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RR1/1

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Harrer A, Pilz G, Wipfler P, Oppermann K, Sellner J, Hitzl W, et al. High interindividual variability in the CD4/CD8 T cell ratio and natalizumab concentration levels in the cerebrospinal fluid of patients with multiple sclerosis. Clin Exp Immunol. 2015;180:383-92 pubmed publisher
	Regal McDonald K, Somarathna M, Lee T, Litovsky S, Barnes J, Peretik J, et al. Assessment of ICAM-1 N-glycoforms in mouse and human models of endothelial dysfunction. PLoS ONE. 2020;15:e0230358 pubmed publisher
	McDonald K, Hernandez Nichols A, BARNES J, Patel R. Hydrogen peroxide regulates endothelial surface N-glycoforms to control inflammatory monocyte rolling and adhesion. Redox Biol. 2020;34:101498 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD54 (ICAM-1) Monoclonal Antibody (RR1/1), eBioscience

Catalog # :

BMS108

Quantity :

50 µg

Price :

US 212

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

RR1/1

Isotype :

IgG1

Storage :

4° C

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

more info or order :

Invitrogen product webpage