Cathepsin L Monoclonal Antibody (33-2), eBioscience | Invitrogen BMS1032 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cathepsin L Monoclonal Antibody (33-2), eBioscience

catalog :

BMS1032

quantity :

100 µg

price :

US 305

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

33-2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, western blot knockout validation

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; 1:100; loading ...; fig s7b	Beumer J, Geurts M, Lamers M, Puschhof J, Zhang J, van der Vaart J, et al. A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses. Nat Commun. 2021;12:5498 pubmed publisher
western blot; human; 1:1000; fig 7	Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cathepsin L Monoclonal Antibody (33-2), eBioscience

Catalog # :

BMS1032

Quantity :

100 µg

Price :

US 305

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Frozen): Assay-Dependent, Western Blot: 1 µg/mL

Species :

Human

Clone :

33-2

Isotype :

IgG1

Storage :

-20°C

Description :

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Frozen): Assay-Dependent, Western Blot: 1 µg/mL

Aliases :

1190035F06Rik; Cat L; cathepsin L; Cathepsin L1; Cathepsin L1 heavy chain; Cathepsin L1 light chain; CATHL; CatL; CP-2; Ctsl; CTSL1; cyclic protein 2; fs; furless; major excreted protein; MEP; nackt; nkt; p39 cysteine proteinase; Procathepsin L

more info or order :

Invitrogen product webpage