BrdU Monoclonal Antibody (MoBU-1), Biotin | Invitrogen B35138 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BrdU Monoclonal Antibody (MoBU-1), Biotin

catalog :

B35138

quantity :

350 µL

price :

US 308.00

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

MoBu-1

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 11

Reference
Mázala D, Novak J, Hogarth M, Nearing M, Adusumalli P, Tully C, et al. TGF-β-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model. JCI Insight. 2020;5: pubmed publisher
Chen S, Li Y, Lin M. Chronic Exposure to the Fusarium Mycotoxin Deoxynivalenol: Impact on Performance, Immune Organ, and Intestinal Integrity of Slow-Growing Chickens. Toxins (Basel). 2017;9: pubmed publisher
Novak J, Hogarth M, Boehler J, Nearing M, Vila M, Heredia R, et al. Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle. Nat Commun. 2017;8:941 pubmed publisher
Cicchini M, Buza E, Sagal K, Gudiel A, Durham A, Feldser D. Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and Progression. Cell Rep. 2017;18:1958-1969 pubmed publisher
Vendetti F, Leibowitz B, Barnes J, Schamus S, Kiesel B, Abberbock S, et al. Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation. Sci Rep. 2017;7:41892 pubmed publisher
Leikina E, Defour A, Melikov K, van der Meulen J, Nagaraju K, Bhuvanendran S, et al. Annexin A1 Deficiency does not Affect Myofiber Repair but Delays Regeneration of Injured Muscles. Sci Rep. 2015;5:18246 pubmed publisher
Coley W, Bogdanik L, Vila M, Yu Q, van der Meulen J, Rayavarapu S, et al. Effect of genetic background on the dystrophic phenotype in mdx mice. Hum Mol Genet. 2016;25:130-45 pubmed publisher
Duddy W, Duguez S, Johnston H, Cohen T, Phadke A, Gordish Dressman H, et al. Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia. Skelet Muscle. 2015;5:16 pubmed publisher
Steel R, Miller J, Sim D, Day D. Delta-9-tetrahydrocannabinol disrupts hippocampal neuroplasticity and neurogenesis in trained, but not untrained adolescent Sprague-Dawley rats. Brain Res. 2014;1548:12-9 pubmed publisher
Kotoshiba S, Gopinathan L, Pfeiffenberger E, Rahim A, Vardy L, Nakayama K, et al. p27 is regulated independently of Skp2 in the absence of Cdk2. Biochim Biophys Acta. 2014;1843:436-45 pubmed publisher
Gualeni B, Rajpar M, Kellogg A, Bell P, Arvan P, Boot Handford R, et al. A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth. Dis Model Mech. 2013;6:1414-25 pubmed publisher

product information

Product Type :

Antibody

Product Name :

BrdU Monoclonal Antibody (MoBU-1), Biotin

Catalog # :

B35138

Quantity :

350 µL

Price :

US 308.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Chemical

Applications :

Immunohistochemistry: Assay-dependent

Species :

Chemical

Clone :

MoBU-1

Isotype :

IgG

Storage :

4° C

Description :

Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.

Immunogen :

BrdU

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-dependent

Aliases :

5-Bromo-2-deoxyuridine; Bromodeoxyuridine

more info or order :

Invitrogen product webpage