This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
BrdU Monoclonal Antibody (MoBU-1), Alexa Fluor 488
catalog :
B35130
quantity :
350 uL
price :
US 542.00
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
MoBu-1
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 42
Reference
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Mao X, Xiong Z, Xue H, Brown M, Gete Y, Yu R, et al. Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome. Int J Mol Sci. 2022;23: pubmed publisher
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Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, et al. ZNF768 links oncogenic RAS to cellular senescence. Nat Commun. 2021;12:4841 pubmed publisher
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Tyler E, Gutierrez Del Arroyo A, Hughes B, Wallis R, Garbe J, Stampfer M, et al. Early growth response 2 (EGR2) is a novel regulator of the senescence programme. Aging Cell. 2021;20:e13318 pubmed publisher
Rodger C, Flex E, Allison R, Sanchis Juan A, Hasenahuer M, Cecchetti S, et al. De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment. Am J Hum Genet. 2020;107:1129-1148 pubmed publisher
Socorro M, Shinde A, Yamazaki H, Khalid S, Monier D, Beniash E, et al. Trps1 transcription factor represses phosphate-induced expression of SerpinB2 in osteogenic cells. Bone. 2020;141:115673 pubmed publisher
Schmid C, Wohnhaas C, Hildebrandt T, Baum P, Rast G. Characterization of iCell cardiomyocytes using single-cell RNA-sequencing methods. J Pharmacol Toxicol Methods. 2020;106:106915 pubmed publisher
Murai J, Zhang H, Pongor L, Tang S, Jo U, Moribe F, et al. Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress. Cell Rep. 2020;30:4137-4151.e6 pubmed publisher
Ali G, Elsayed A, Nandakumar M, BASHIR M, Younis I, Abu Aqel Y, et al. Keratinocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Genetic Signature of Psoriasis Disease. Stem Cells Dev. 2020;29:383-400 pubmed publisher
Li Y, Ruan X, Xu X, Li C, Qiang T, Zhou H, et al. Shengmai Injection Suppresses Angiotensin II-Induced Cardiomyocyte Hypertrophy and Apoptosis via Activation of the AMPK Signaling Pathway Through Energy-Dependent Mechanisms. Front Pharmacol. 2019;10:1095 pubmed publisher
Perl A, O Connor C, Fa P, Mayca Pozo F, Zhang J, Zhang Y, et al. Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45). J Biol Chem. 2019;294:17043-17059 pubmed publisher
Bigot N, Day M, Baldock R, Watts F, Oliver A, Pearl L. Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. elife. 2019;8: pubmed publisher
Dias M, Fonseca C, Zeidler J, Albuquerque L, Da Silva M, Cararo Lopes E, et al. Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors. Mol Oncol. 2019;13:290-306 pubmed publisher
Nepon Sixt B, Alexandrow M. TGFβ1 Cell Cycle Arrest Is Mediated by Inhibition of MCM Assembly in Rb-Deficient Conditions. Mol Cancer Res. 2019;17:277-288 pubmed publisher
Sourbier C, Liao P, Ricketts C, Wei D, Yang Y, Baranes S, et al. Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers. Oncotarget. 2018;9:10723-10733 pubmed publisher
Morita Y, Ohno M, Nishi K, Hiraoka Y, Saijo S, Matsuda S, et al. Genome-wide profiling of nardilysin target genes reveals its role in epigenetic regulation and cell cycle progression. Sci Rep. 2017;7:14801 pubmed publisher
Yang Y, Vocke C, Ricketts C, Wei D, Padilla Nash H, Lang M, et al. Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276). Genes Chromosomes Cancer. 2017;56:719-729 pubmed publisher
Tsoi H, Lam K, Dong Y, Zhang X, Lee C, Zhang J, et al. Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients. Oncogene. 2017;36:6109-6118 pubmed publisher
Busada J, Velte E, Serra N, Cook K, Niedenberger B, Willis W, et al. Rhox13 is required for a quantitatively normal first wave of spermatogenesis in mice. Reproduction. 2016;152:379-88 pubmed publisher
Boufraqech M, Wei D, Weyemi U, Zhang L, Quezado M, Kalab P, et al. LOX is a novel mitotic spindle-associated protein essential for mitosis. Oncotarget. 2016;7:29023-35 pubmed publisher
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Rostama B, Turner J, Seavey G, Norton C, Gridley T, Vary C, et al. DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1. Arterioscler Thromb Vasc Biol. 2015;35:2626-37 pubmed publisher
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Zhu J, Su F, Mukherjee S, Mori E, Hu B, Asaithamby A. FANCD2 influences replication fork processes and genome stability in response to clustered DSBs. Cell Cycle. 2015;14:1809-22 pubmed publisher
Vinue A, Andrés Blasco I, Herrero Cervera A, Piqueras L, Andres V, Burks D, et al. Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling. Biochim Biophys Acta. 2015;1852:1729-42 pubmed publisher
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Dimitrova N, Zamudio J, Jong R, Soukup D, Resnick R, Sarma K, et al. LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint. Mol Cell. 2014;54:777-90 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
BrdU Monoclonal Antibody (MoBU-1), Alexa Fluor 488
Catalog # :
B35130
Quantity :
350 uL
Price :
US 542.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Chemical
Applications :
Immunohistochemistry: Assay-dependent
Species :
Chemical
Clone :
MoBU-1
Isotype :
IgG
Storage :
4 C
Description :
Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.
Immunogen :
BrdU
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: Assay-dependent
Aliases :
5-Bromo-2-deoxyuridine; Bromodeoxyuridine
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA