BrdU Monoclonal Antibody (MoBU-1), Pacific Blue | Invitrogen B35129 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BrdU Monoclonal Antibody (MoBU-1), Pacific Blue

catalog :

B35129

quantity :

100 Tests

price :

US 546.00

clonality :

monoclonal

host :

mouse

conjugate :

Pacific Blue

clone name :

MoBu-1

application :

flow cytometry

citations: 13

Reference
Conte M, Poli M, Taglialatela A, Leuzzi G, Chinn I, Salinas S, et al. Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia. JCI Insight. 2022;7: pubmed publisher
Li T, Wang X, Ju E, da Silva S, Chen L, Zhang X, et al. RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nat Commun. 2021;12:1055 pubmed publisher
Li T, Ju E, Gao S. Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis. J Clin Invest. 2019;129:3310-3323 pubmed publisher
Gruffaz M, Yuan H, Meng W, Liu H, Bae S, Kim J, et al. CRISPR-Cas9 Screening of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells. MBio. 2019;10: pubmed publisher
Dumm R, Fiege J, Waring B, Kuo C, Langlois R, Heaton N. Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function. Nat Commun. 2019;10:779 pubmed publisher
Stewart I, Radtke D, Phillips B, McGowan S, Bannard O. Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging. Immunity. 2018;49:477-489.e7 pubmed publisher
Gruffaz M, Zhou S, Vasan K, Rushing T, Michael Q, Lu C, et al. Repurposing Cytarabine for Treating Primary Effusion Lymphoma by Targeting Kaposi's Sarcoma-Associated Herpesvirus Latent and Lytic Replications. MBio. 2018;9: pubmed publisher
He M, Tan B, Vasan K, Yuan H, Cheng F, Ramos da Silva S, et al. SIRT1 and AMPK pathways are essential for the proliferation and survival of primary effusion lymphoma cells. J Pathol. 2017;242:309-321 pubmed publisher
Yuan H, He M, Cheng F, Bai R, da Silva S, Aguiar R, et al. Tenovin-6 inhibits proliferation and survival of diffuse large B-cell lymphoma cells by blocking autophagy. Oncotarget. 2017;8:14912-14924 pubmed publisher
He M, Yuan H, Tan B, Bai R, Kim H, Bae S, et al. SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells. Oncotarget. 2016;7:75698-75711 pubmed publisher
Zhu Y, Ramos da Silva S, He M, Liang Q, Lu C, Feng P, et al. An Oncogenic Virus Promotes Cell Survival and Cellular Transformation by Suppressing Glycolysis. PLoS Pathog. 2016;12:e1005648 pubmed publisher
Funakoshi S, Shimizu T, Numata O, Ato M, Melchers F, Ohnishi K. BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. PLoS ONE. 2015;10:e0117566 pubmed publisher
HERNANDEZ V, Weng J, Ly P, Pompey S, Dong H, Mishra L, et al. Cavin-3 dictates the balance between ERK and Akt signaling. elife. 2013;2:e00905 pubmed publisher

product information

Product Type :

Antibody

Product Name :

BrdU Monoclonal Antibody (MoBU-1), Pacific Blue

Catalog # :

B35129

Quantity :

100 Tests

Price :

US 546.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Chemical

Applications :

Flow Cytometry: Assay-dependent

Species :

Chemical

Clone :

MoBU-1

Isotype :

IgG

Storage :

4 C

Description :

Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.

Immunogen :

BrdU

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent

Aliases :

5-Bromo-2-deoxyuridine; Bromodeoxyuridine