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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
BrdU Monoclonal Antibody (MoBU-1)
catalog :
B35128
quantity :
350 µL
price :
US 267.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MoBu-1
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 56
Reference
Lee M, Wan J, Goldman D. Tgfb3 collaborates with PP2A and notch signaling pathways to inhibit retina regeneration. elife. 2020;9: pubmed publisher
Morales Torres C, Wu M, Hobor S, Wainwright E, Martin M, Patel H, et al. Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nat Commun. 2020;11:1792 pubmed publisher
Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, et al. The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019;7:199 pubmed publisher
Roy A, Ghosh A, Kumar B, Chandran B. IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. elife. 2019;8: pubmed publisher
Arreal L, Piva M, Fernandez S, Revandkar A, Schaub Clerigué A, Villanueva J, et al. Targeting PML in triple negative breast cancer elicits growth suppression and senescence. Cell Death Differ. 2019;: pubmed publisher
Perl A, O Connor C, Fa P, Mayca Pozo F, Zhang J, Zhang Y, et al. Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45). J Biol Chem. 2019;294:17043-17059 pubmed publisher
Huycke T, Miller B, Gill H, Nerurkar N, Sprinzak D, Mahadevan L, et al. Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development. Cell. 2019;179:90-105.e21 pubmed publisher
Kureel S, Mogha P, Khadpekar A, Kumar V, Joshi R, Das S, et al. Soft substrate maintains proliferative and adipogenic differentiation potential of human mesenchymal stem cells on long-term expansion by delaying senescence. Biol Open. 2019;8: pubmed publisher
Larson T, Thatra N, Hou D, Hu R, Brenowitz E. Seasonal changes in neuronal turnover in a forebrain nucleus in adult songbirds. J Comp Neurol. 2019;527:767-779 pubmed publisher
Mineyeva O, Bezriadnov D, Kedrov A, Lazutkin A, Anokhin K, ENIKOLOPOV G. Radiation Induces Distinct Changes in Defined Subpopulations of Neural Stem and Progenitor Cells in the Adult Hippocampus. Front Neurosci. 2018;12:1013 pubmed publisher
James K, Cosway E, LUCAS B, White A, Parnell S, Carvalho Gaspar M, et al. Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration. J Exp Med. 2018;215:2984-2993 pubmed publisher
Disson O, Blériot C, Jacob J, Serafini N, Dulauroy S, Jouvion G, et al. Peyer's patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion. J Exp Med. 2018;215:2936-2954 pubmed publisher
Valcarcel Jimenez L, Macchia A, Martin Martin N, Cortazar A, Schaub Clerigué A, Pujana Vaquerizo M, et al. Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer. Cell Death Dis. 2018;9:1041 pubmed publisher
Stallings C, Ellsworth B. Premature Expression of FOXO1 in Developing Mouse Pituitary Results in Anterior Lobe Hypoplasia. Endocrinology. 2018;159:2891-2904 pubmed publisher
De Jong D, Seaver E. Investigation into the cellular origins of posterior regeneration in the annelid Capitella teleta. Regeneration (Oxf). 2018;5:61-77 pubmed publisher
Chen C, Zhai S, Zhang L, Chen J, Long X, Qin J, et al. Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection. J Exp Med. 2018;215:1437-1448 pubmed publisher
Atkinson P, Dong Y, Gu S, Liu W, Najarro E, Udagawa T, et al. Sox2 haploinsufficiency primes regeneration and Wnt responsiveness in the mouse cochlea. J Clin Invest. 2018;128:1641-1656 pubmed publisher
Mineyeva O, Enikolopov G, Koulakov A. Spatial geometry of stem cell proliferation in the adult hippocampus. Sci Rep. 2018;8:3444 pubmed publisher
Norum J, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, et al. The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology. Biol Res. 2018;51:3 pubmed publisher
Mayer C, Gazumyan A, Kara E, Gitlin A, Golijanin J, Viant C, et al. The microanatomic segregation of selection by apoptosis in the germinal center. Science. 2017;358: pubmed publisher
Kumagai A, Dunphy W. MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication. Mol Biol Cell. 2017;28:2998-3012 pubmed publisher
Zape J, Lizama C, Cautivo K, Zovein A. Cell cycle dynamics and complement expression distinguishes mature haematopoietic subsets arising from hemogenic endothelium. Cell Cycle. 2017;16:1835-1847 pubmed publisher
Rich B, Scadeng M, Yamaguchi M, Wagner P, Breen E. Skeletal myofiber vascular endothelial growth factor is required for the exercise training-induced increase in dentate gyrus neuronal precursor cells. J Physiol. 2017;595:5931-5943 pubmed publisher
Barazzuol L, Ju L, Jeggo P. A coordinated DNA damage response promotes adult quiescent neural stem cell activation. PLoS Biol. 2017;15:e2001264 pubmed publisher
Ligasová A, Konecny P, Frydrych I, Koberna K. Cell cycle profiling by image and flow cytometry: The optimised protocol for the detection of replicational activity using 5-Bromo-2'-deoxyuridine, low concentration of hydrochloric acid and exonuclease III. PLoS ONE. 2017;12:e0175880 pubmed publisher
Fan Y, Mok C, Chan M, Zhang Y, Nal B, Kien F, et al. Cell Cycle-independent Role of Cyclin D3 in Host Restriction of Influenza Virus Infection. J Biol Chem. 2017;292:5070-5088 pubmed publisher
Nagaraj R, Sharpley M, Chi F, Braas D, Zhou Y, Kim R, et al. Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation. Cell. 2017;168:210-223.e11 pubmed publisher
Ju X, Hou Q, Sheng A, Wu K, Zhou Y, Jin Y, et al. The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. elife. 2016;5: pubmed publisher
Smither B, Pang H, Brubaker P. Glucagon-Like Peptide-2 Requires a Full Complement of Bmi-1 for Its Proliferative Effects in the Murine Small Intestine. Endocrinology. 2016;157:2660-70 pubmed publisher
Paine I, Chauvière A, Landua J, Sreekumar A, Cristini V, Rosen J, et al. A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud. PLoS Comput Biol. 2016;12:e1004839 pubmed publisher
Pierzyńska Mach A, Szczurek A, Cella Zanacchi F, Pennacchietti F, Drukała J, Diaspro A, et al. Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy. Cell Cycle. 2016;15:1156-67 pubmed publisher
Al Taweel F, Douglas C, Whawell S. The Periodontal Pathogen Porphyromonas gingivalis Preferentially Interacts with Oral Epithelial Cells in S Phase of the Cell Cycle. Infect Immun. 2016;84:1966-1974 pubmed publisher
Nomura T, Ohtaka Maruyama C, Yamashita W, Wakamatsu Y, Murakami Y, Calegari F, et al. The evolution of basal progenitors in the developing non-mammalian brain. Development. 2016;143:66-74 pubmed publisher
Thuret R, Auger H, Papalopulu N. Analysis of neural progenitors from embryogenesis to juvenile adult in Xenopus laevis reveals biphasic neurogenesis and continuous lengthening of the cell cycle. Biol Open. 2015;4:1772-81 pubmed publisher
Lo C, Weil B, Palka B, Momeni A, Canty J, Neelamegham S. Cell surface glycoengineering improves selectin-mediated adhesion of mesenchymal stem cells (MSCs) and cardiosphere-derived cells (CDCs): Pilot validation in porcine ischemia-reperfusion model. Biomaterials. 2016;74:19-30 pubmed publisher
Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, et al. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes Dev. 2015;29:1955-68 pubmed publisher
Massey A. Multiparametric Cell Cycle Analysis Using the Operetta High-Content Imager and Harmony Software with PhenoLOGIC. PLoS ONE. 2015;10:e0134306 pubmed publisher
Rybak P, Waligórska A, Bujnowicz Ł, Hoang A, Dobrucki J. Activation of new replication foci under conditions of replication stress. Cell Cycle. 2015;14:2634-47 pubmed publisher
Calderon M, Ploegman A, Bailey B, Jung D, Navratil A, Ellsworth B. Loss of Foxm1 Results in Reduced Somatotrope Cell Number during Mouse Embryogenesis. PLoS ONE. 2015;10:e0128942 pubmed publisher
Watanabe N, Kageyama R, Ohtsuka T. Hbp1 regulates the timing of neuronal differentiation during cortical development by controlling cell cycle progression. Development. 2015;142:2278-90 pubmed publisher
Shen Z, Stanger B. YAP regulates S-phase entry in endothelial cells. PLoS ONE. 2015;10:e0117522 pubmed publisher
Urness L, Wang X, Shibata S, Ohyama T, Mansour S. Fgf10 is required for specification of non-sensory regions of the cochlear epithelium. Dev Biol. 2015;400:59-71 pubmed publisher
Holder G, McGary C, Johnson E, Zheng R, John V, Sugimoto C, et al. Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection. J Neuroimmune Pharmacol. 2014;9:716-26 pubmed publisher
Clewell R, Sun B, Adeleye Y, Carmichael P, Efremenko A, McMullen P, et al. Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage. Toxicol Sci. 2014;142:56-73 pubmed publisher
White R, Holdaway B, Moody J, Chang Y. Chronic Caffeine Administration Attenuates Vascular Injury-Induced Neointimal Hyperplasia in Rats. J Caffeine Res. 2013;3:163-168 pubmed
Delavar H, Nogueira L, Wagner P, Hogan M, Metzger D, Breen E. Skeletal myofiber VEGF is essential for the exercise training response in adult mice. Am J Physiol Regul Integr Comp Physiol. 2014;306:R586-95 pubmed publisher
Yu H, Pak H, Hammond Martel I, Ghram M, Rodrigue A, Daou S, et al. Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair. Proc Natl Acad Sci U S A. 2014;111:285-90 pubmed publisher
Ragland R, Patel S, Rivard R, Smith K, Peters A, Bielinsky A, et al. RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells. Genes Dev. 2013;27:2259-73 pubmed publisher
Alunni A, Krecsmarik M, Bosco A, Galant S, Pan L, Moens C, et al. Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development. 2013;140:3335-47 pubmed publisher
Liu B, Staron M, Hong F, Wu B, Sun S, Morales C, et al. Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway. Proc Natl Acad Sci U S A. 2013;110:6877-82 pubmed publisher
Jia S, Gao X, Lee S, Maira S, Wu X, Stack E, et al. Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention. Cancer Discov. 2013;3:44-51 pubmed publisher
Holy M, Brautigan D. Calyculin A from Discodermia calyx is a dual action toxin that blocks calcium influx and inhibits protein Ser/Thr phosphatases. Toxins (Basel). 2012;4:940-54 pubmed publisher
Garrod K, Moreau H, Garcia Z, Lemaitre F, Bouvier I, Albert M, et al. Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis. Cell Rep. 2012;2:1438-47 pubmed publisher
Auger H, Thuret R, El Yakoubi W, Papalopulu N. A bromodeoxyuridine (BrdU) based protocol for characterizing proliferating progenitors in Xenopus embryos. Methods Mol Biol. 2012;917:461-75 pubmed publisher
Tour G, Wendel M, Tcacencu I. Bone marrow stromal cells enhance the osteogenic properties of hydroxyapatite scaffolds by modulating the foreign body reaction. J Tissue Eng Regen Med. 2014;8:841-9 pubmed publisher
Peterson S, Li Y, Chait B, Gottesman M, Baer R, Gautier J. Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair. J Cell Biol. 2011;194:705-20 pubmed publisher
product information
Product Type :
Antibody
Product Name :
BrdU Monoclonal Antibody (MoBU-1)
Catalog # :
B35128
Quantity :
350 µL
Price :
US 267.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Chemical
Applications :
Immunohistochemistry: Assay-dependent
Species :
Chemical
Clone :
MoBU-1
Isotype :
IgG
Storage :
4° C
Description :
Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.
Immunogen :
BrdU
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: Assay-dependent
Aliases :
5-Bromo-2-deoxyuridine; Bromodeoxyuridine
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA