IL-10 Monoclonal Antibody (945A1A926C2), Biotin | Invitrogen ASC9109 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-10 Monoclonal Antibody (945A1A926C2), Biotin

catalog :

ASC9109

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

945A1A926C2

reactivity :

pigs

application :

ELISA, flow cytometry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; pigs ; fig s2	Rajão D, Sandbulte M, Gauger P, Kitikoon P, Platt R, Roth J, et al. Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory disease in weaned piglets. Virology. 2016;491:79-88 pubmed publisher
flow cytometry; pigs	Platt R, Vincent A, Gauger P, Loving C, Zanella E, Lager K, et al. Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs. Vet Immunol Immunopathol. 2011;142:252-7 pubmed publisher
ELISA; pigs ; fig 3	Fort M, Sibila M, Nofrarias M, Perez Martín E, Olvera A, Mateu E, et al. Porcine circovirus type 2 (PCV2) Cap and Rep proteins are involved in the development of cell-mediated immunity upon PCV2 infection. Vet Immunol Immunopathol. 2010;137:226-34 pubmed publisher
flow cytometry; pigs ; fig 5	Jamin A, Gorin S, Le Potier M, Kuntz Simon G. Characterization of conventional and plasmacytoid dendritic cells in swine secondary lymphoid organs and blood. Vet Immunol Immunopathol. 2006;114:224-37 pubmed
ELISA; pigs ; fig 3	Barnard A, Arriens A, Cox S, Barnett P, Kristensen B, Summerfield A, et al. Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease. Vaccine. 2005;23:1037-47 pubmed
	Trus I, Walker S, Fuchs M, Udenze D, Gerdts V, Karniychuk U. A Porcine Model of Zika Virus Infection to Profile the In Utero Interferon Alpha Response. Methods Mol Biol. 2020;2142:181-195 pubmed publisher
	Pasternak J, Ng S, Buchanan R, Mertins S, Mutwiri G, Gerdts V, et al. Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life. BMC Vet Res. 2015;11:50 pubmed publisher
	Bongoni A, Lanz J, Rieben R, Banz Y. Development of a bead-based multiplex assay for the simultaneous detection of porcine inflammation markers using xMAP technology. Cytometry A. 2013;83:636-47 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL-10 Monoclonal Antibody (945A1A926C2), Biotin

Catalog # :

ASC9109

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Porcine

Applications :

ELISA: Assay-dependent

Species :

Porcine

Clone :

945A1A926C2

Isotype :

IgG1, kappa

Storage :

-20 C

Description :

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

Immunogen :

Recombinant swine IL-10.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

more info or order :

Invitrogen product webpage