IL-10 Monoclonal Antibody (945A4C437B1) | Invitrogen ASC0104 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-10 Monoclonal Antibody (945A4C437B1)

catalog :

ASC0104

quantity :

500 µg

price :

US 430

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

945A4C437B1

reactivity :

pigs

application :

immunocytochemistry, flow cytometry, blocking or activating experiments

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; pigs	Suradhat S, Wongyanin P, Kesdangsakonwut S, Teankum K, Lumyai M, Triyarach S, et al. A novel DNA vaccine for reduction of PRRSV-induced negative immunomodulatory effects: A proof of concept. Vaccine. 2015;33:3997-4003 pubmed publisher
ELISA; pigs	Ladinig A, Lunney J, Souza C, Ashley C, Plastow G, Harding J. Cytokine profiles in pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus and relationships with viral load and fetal outcome. Vet Res. 2014;45:113 pubmed publisher
immunocytochemistry; pigs	Knetter S, Tuggle C, Wannemuehler M, Ramer Tait A. Organic barn dust extract exposure impairs porcine macrophage function in vitro: implications for respiratory health. Vet Immunol Immunopathol. 2014;157:20-30 pubmed publisher
blocking or activating experiments; pigs	Charerntantanakul W, Platt R, Roth J. Effects of porcine reproductive and respiratory syndrome virus-infected antigen-presenting cells on T cell activation and antiviral cytokine production. Viral Immunol. 2006;19:646-61 pubmed
flow cytometry; pigs ; fig 3	Suradhat S, Kesdangsakonwut S, Sada W, Buranapraditkun S, Wongsawang S, Thanawongnuwech R. Negative impact of porcine reproductive and respiratory syndrome virus infection on the efficacy of classical swine fever vaccine. Vaccine. 2006;24:2634-42 pubmed
flow cytometry; pigs	Suradhat S, Sada W, Buranapraditkun S, Damrongwatanapokin S. The kinetics of cytokine production and CD25 expression by porcine lymphocyte subpopulations following exposure to classical swine fever virus (CSFV). Vet Immunol Immunopathol. 2005;106:197-208 pubmed
ELISA; pigs ; fig 3	Barnard A, Arriens A, Cox S, Barnett P, Kristensen B, Summerfield A, et al. Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease. Vaccine. 2005;23:1037-47 pubmed
	Trus I, Walker S, Fuchs M, Udenze D, Gerdts V, Karniychuk U. A Porcine Model of Zika Virus Infection to Profile the In Utero Interferon Alpha Response. Methods Mol Biol. 2020;2142:181-195 pubmed publisher
	Pasternak J, Ng S, Buchanan R, Mertins S, Mutwiri G, Gerdts V, et al. Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life. BMC Vet Res. 2015;11:50 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL-10 Monoclonal Antibody (945A4C437B1)

Catalog # :

ASC0104

Quantity :

500 µg

Price :

US 430

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Porcine

Applications :

ELISA: Assay-dependent

Species :

Porcine

Clone :

945A4C437B1

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

Immunogen :

Recombinant swine IL-10.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF