IL-4 Monoclonal Antibody (BVD4-1D11) | Invitrogen AMC0042 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-4 Monoclonal Antibody (BVD4-1D11)

catalog :

AMC0042

quantity :

500 µg

price :

US 375.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

BVD4-1D11

reactivity :

mouse

application :

ELISA, neutralization, flow cytometry

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
ELISA; mouse	Murai H, Qi H, Choudhury B, Wild J, Dharajiya N, Vaidya S, et al. Alternaria-induced release of IL-18 from damaged airway epithelial cells: an NF-?B dependent mechanism of Th2 differentiation?. PLoS ONE. 2012;7:e30280 pubmed publisher
ELISA; mouse; fig 4	Al Qaoud K, Abdel Hafez S. Humoral and cytokine response during protection of mice against secondary hydatidosis caused by Echinococcus granulosus. Parasitol Res. 2005;98:54-60 pubmed
flow cytometry; mouse; fig 4	Minami K, Yanagawa Y, Iwabuchi K, Shinohara N, Harabayashi T, Nonomura K, et al. Negative feedback regulation of T helper type 1 (Th1)/Th2 cytokine balance via dendritic cell and natural killer T cell interactions. Blood. 2005;106:1685-93 pubmed
ELISA; mouse; fig 6	Chida Y, Sudo N, Kubo C. Social isolation stress exacerbates autoimmune disease in MRL/lpr mice. J Neuroimmunol. 2005;158:138-44 pubmed
ELISA; mouse; fig 5	Couillin I, Maillet I, Vargaftig B, Jacobs M, Paesen G, Nuttall P, et al. Arthropod-derived histamine-binding protein prevents murine allergic asthma. J Immunol. 2004;173:3281-6 pubmed
ELISA; mouse	Cabarrocas J, Piaggio E, Zappulla J, Desbois S, Mars L, Lassmann H, et al. A transgenic mouse model for T-cell ignorance of a glial autoantigen. J Autoimmun. 2004;22:179-89 pubmed
ELISA; mouse; fig 2	Kuroda E, Yamashita U. Assay system for the effect of prostaglandin E(2) in the determination of polarized cytokine production. Methods Mol Biol. 2004;249:229-38 pubmed
flow cytometry; mouse	Matsuda J, Gapin L, Baron J, Sidobre S, Stetson D, Mohrs M, et al. Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo. Proc Natl Acad Sci U S A. 2003;100:8395-400 pubmed
flow cytometry; mouse	Kikuchi K, Yanagawa Y, Aranami T, Iwabuchi C, Iwabuchi K, Onoe K. Tumour necrosis factor-alpha but not lipopolysaccharide enhances preference of murine dendritic cells for Th2 differentiation. Immunology. 2003;108:42-9 pubmed
ELISA; mouse; tbl 2	Wizel B, Starcher B, Samten B, Chroneos Z, Barnes P, Dzuris J, et al. Multiple Chlamydia pneumoniae antigens prime CD8+ Tc1 responses that inhibit intracellular growth of this vacuolar pathogen. J Immunol. 2002;169:2524-35 pubmed
flow cytometry; mouse; fig 4	Jankovic D, Kullberg M, Noben Trauth N, Caspar P, Paul W, Sher A. Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile. J Immunol. 2000;164:3047-55 pubmed
	Kummola L, Ortutay Z, Chen X, Caucheteux S, HÃ¤mÃ¤lÃ¤inen S, AittomÃ¤ki S, et al. IL-7RÎ± Expression Regulates Murine Dendritic Cell Sensitivity to Thymic Stromal Lymphopoietin. J Immunol. 2017;198:3909-3918 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL-4 Monoclonal Antibody (BVD4-1D11)

Catalog # :

AMC0042

Quantity :

500 µg

Price :

US 375.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rat

Reactivity :

Mouse

Applications :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Neutralization: Assay-dependent

Species :

Mouse

Clone :

BVD4-1D11

Isotype :

IgG2b

Storage :

-20°C

Description :

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

Immunogen :

Recombinant mouse IL-4.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Neutralization: Assay-dependent

Aliases :

B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

more info or order :

Invitrogen product webpage