product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
beta Actin Monoclonal Antibody (AC-15)
catalog :
AM4302
quantity :
100 µg
price :
US 306
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AC-15
reactivity :
guinea pig, hamsters, human, mouse, dogs, chicken, bovine, pigs , cat, domestic sheep, domestic rabbit
application :
western blot, immunocytochemistry
more info or order :
citations: 102
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 1b
Kang Y, Torrente L, Falzone A, Elkins C, Liu M, Asara J, et al. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. elife. 2019;8: pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 4b
de Oliveira R, Vicente Miranda H, Francelle L, Pinho R, Szego E, Martinho R, et al. The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biol. 2017;15:e2000374 pubmed publisher
  • western blot; mouse; 1:20,000; loading ...; fig 1a
Muranen T, Iwanicki M, Curry N, Hwang J, DuBois C, Coloff J, et al. Starved epithelial cells uptake extracellular matrix for survival. Nat Commun. 2017;8:13989 pubmed publisher
  • western blot; human; fig 5
Alcoba D, Schneider J, Arruda L, Martiny P, Capp E, von Eye Corleta H, et al. Brilliant cresyl blue staining does not present cytotoxic effects on human luteinized follicular cells, according to gene/protein expression, as well as to cytotoxicity tests. Reprod Biol. 2017;17:60-68 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2b
Echevarria F, Rickman A, Sappington R. Interleukin-6: A Constitutive Modulator of Glycoprotein 130, Neuroinflammatory and Cell Survival Signaling in Retina. J Clin Cell Immunol. 2016;7: pubmed
  • western blot; chicken; fig s4
Romanello M, Schiavone D, Frey A, Sale J. Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA. EMBO J. 2016;35:1452-64 pubmed publisher
  • western blot; human; 1:20,000; fig 2
You J, Sobreira N, Gable D, Jurgens J, Grange D, Belnap N, et al. A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex. Am J Hum Genet. 2016;98:909-918 pubmed publisher
  • western blot; human; fig 3
Okumura F, Uematsu K, Byrne S, Hirano M, Joo Okumura A, Nishikimi A, et al. Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor ?. Mol Cell Biol. 2016;36:1803-17 pubmed publisher
  • western blot; human; fig 4
Conery A, Centore R, Neiss A, Keller P, Joshi S, Spillane K, et al. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. elife. 2016;5: pubmed publisher
  • western blot; human; fig 3
Jin Y, Andrade J, Wickstrom E. Non-Specific Blocking of miR-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity. PLoS ONE. 2015;10:e0142574 pubmed publisher
  • western blot; human; 1:5000; fig 2
Oliveira L, Falomir Lockhart L, Botelho M, Lin K, Wales P, Koch J, et al. Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells. Cell Death Dis. 2015;6:e1994 pubmed publisher
  • western blot; human; 1:20,000; fig 1
Mircsof D, Langouët M, Rio M, Moutton S, Siquier Pernet K, Bole Feysot C, et al. Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects. Nat Neurosci. 2015;18:1731-6 pubmed publisher
  • western blot; human; fig s1
Deisting W, Raum T, Kufer P, Baeuerle P, Münz M. Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110. PLoS ONE. 2015;10:e0141669 pubmed publisher
  • western blot; human; 1:250
Mello A, Leal M, Rey J, Pinto G, Lamarão L, Montenegro R, et al. Deregulated Expression of SRC, LYN and CKB Kinases by DNA Methylation and Its Potential Role in Gastric Cancer Invasiveness and Metastasis. PLoS ONE. 2015;10:e0140492 pubmed publisher
  • western blot; mouse; 1:3000
Golden E, Benito Gonzalez A, Doetzlhofer A. The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015;112:E3864-73 pubmed publisher
  • immunocytochemistry; human
Powell J, Hutchison J, Hess B, Straub T. Bacillus anthracis spores germinate extracellularly at air-liquid interface in an in vitro lung model under serum-free conditions. J Appl Microbiol. 2015;119:711-23 pubmed publisher
  • western blot; bovine; fig 5
Bowdridge E, Goravanahally M, Inskeep E, Flores J. Activation of Adenosine Monophosphate-Activated Protein Kinase Is an Additional Mechanism That Participates in Mediating Inhibitory Actions of Prostaglandin F2Alpha in Mature, but Not Developing, Bovine Corpora Lutea. Biol Reprod. 2015;93:7 pubmed publisher
  • western blot; human; 1:10,000; fig 3a
Janes K. An analysis of critical factors for quantitative immunoblotting. Sci Signal. 2015;8:rs2 pubmed publisher
  • western blot; human; fig 3
de Lucas Cerrillo A, Bond W, Rex T. Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin. Gene Ther. 2015;22:365-73 pubmed publisher
  • western blot; mouse; 1:5000; fig 4c
Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour M, et al. Cyclin C is a haploinsufficient tumour suppressor. Nat Cell Biol. 2014;16:1080-91 pubmed publisher
  • western blot; human
Han Z, Jing Y, Xia Y, Zhang S, Hou J, Meng Y, et al. Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy. Cell Biosci. 2014;4:22 pubmed publisher
  • western blot; hamsters
Jafari M, Xu W, Pan R, Sweeting C, Karunaratne D, Chen P. Serum stability and physicochemical characterization of a novel amphipathic peptide C6M1 for siRNA delivery. PLoS ONE. 2014;9:e97797 pubmed publisher
  • western blot; human
Johnson S, Collins J, D Souza V, Telesnitsky A. Determinants of Moloney murine leukemia virus Gag-Pol and genomic RNA proportions. J Virol. 2014;88:7267-75 pubmed publisher
  • western blot; human; 1:1000
Wang C, Bajikar S, Jamal L, Atkins K, Janes K. A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies. Nat Cell Biol. 2014;16:345-56 pubmed publisher
  • western blot; bovine; 1:2000
Wright M, Bowdridge E, McDermott E, Richardson S, Scheidler J, Syed Q, et al. Mechanisms of intracellular calcium homeostasis in developing and mature bovine corpora lutea. Biol Reprod. 2014;90:55 pubmed publisher
  • western blot; mouse; fig 6
Lavado A, He Y, Pare J, Neale G, Olson E, Giovannini M, et al. Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013;140:3323-34 pubmed publisher
  • western blot; mouse; 3 ug/ml
Sims S, Holmgren L, Cathcart H, Sappington R. Spatial regulation of interleukin-6 signaling in response to neurodegenerative stressors in the retina. Am J Neurodegener Dis. 2012;1:168-79 pubmed
  • western blot; human; 1:1000; fig 7
Cheung T, Ganatra M, Peters E, Truskey G. Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells. Am J Physiol Heart Circ Physiol. 2012;303:H1374-83 pubmed publisher
  • western blot; human; 1:5000; fig 2
Johnson S, Garcia E, Summers M, Telesnitsky A. Moloney murine leukemia virus genomic RNA packaged in the absence of a full complement of wild type nucleocapsid protein. Virology. 2012;430:100-9 pubmed publisher
  • western blot; mouse; fig 1
Liu X, Ko S, Xu Y, Fattah E, Xiang Q, Jagannath C, et al. Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress. J Biol Chem. 2012;287:19687-98 pubmed publisher
Kim J, Bryant H, Fiedler E, Cao T, Rayner J. Real-time tracking of bioluminescent influenza A virus infection in mice. Sci Rep. 2022;12:3152 pubmed publisher
Yang Y, Chan W. Glycogen Synthase Kinase 3 Beta Regulates the Human Aryl Hydrocarbon Receptor Cellular Content and Activity. Int J Mol Sci. 2021;22: pubmed publisher
Kilgas S, Singh A, Paillas S, Then C, Torrecilla I, Nicholson J, et al. p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation. Cell Rep. 2021;35:109153 pubmed publisher
Chen J, Yang Y, Russu W, Chan W. The Aryl Hydrocarbon Receptor Undergoes Chaperone-Mediated Autophagy in Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2021;22: pubmed publisher
Wanschel A, Guizoni D, Lorza Gil E, Salerno A, Paiva A, Dorighello G, et al. The Presence of Cholesteryl Ester Transfer Protein (CETP) in Endothelial Cells Generates Vascular Oxidative Stress and Endothelial Dysfunction. Biomolecules. 2021;11: pubmed publisher
Ucuncu E, Rajamani K, Wilson M, Medina Cano D, Altin N, David P, et al. MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia. Nat Commun. 2020;11:6087 pubmed publisher
Li Y, Bai J, Yang Y, Hoshi N, Chen D. Hydrogen Sulfide Relaxes Human Uterine Artery via Activating Smooth Muscle BKCa Channels. Antioxidants (Basel). 2020;9: pubmed publisher
Zhu S, Law A, Deng R, Poon E, Lo C, Kwong A, et al. Generation of genomic-integration-free human induced pluripotent stem cells and the derived cardiomyocytes of X-linked dilated cardiomyopathy from DMD gene mutation. Stem Cell Res. 2020;49:102040 pubmed publisher
Chen C, Hsu C, Lin H, Zeng H, Cheng K, Wu C, et al. KRAS K104 modification affects the KRASG12D-GEF interaction and mediates cell growth and motility. Sci Rep. 2020;10:17447 pubmed publisher
Zhou J, Zhang A, Fan L. HSPA12B Secreted by Tumor-Associated Endothelial Cells Might Induce M2 Polarization of Macrophages via Activating PI3K/Akt/mTOR Signaling. Onco Targets Ther. 2020;13:9103-9111 pubmed publisher
Koepke L, Winter B, Grenzner A, Regensburger K, Engelhart S, van der Merwe J, et al. An improved method for high-throughput quantification of autophagy in mammalian cells. Sci Rep. 2020;10:12241 pubmed publisher
Chintala S, Levan J, Robinson K, Quist K, Katzenellenbogen R. Genes Regulated by HPV 16 E6 and High Expression of NFX1-123 in Cervical Cancers. Onco Targets Ther. 2020;13:6143-6156 pubmed publisher
Kang Y, Falzone A, Liu M, González Sánchez P, Choi B, Coloff J, et al. PHGDH supports liver ceramide synthesis and sustains lipid homeostasis. Cancer Metab. 2020;8:6 pubmed publisher
Boyt D, Boland L, Burand A, Brown A, Ankrum J. Dose and duration of interferon γ pre-licensing interact with donor characteristics to influence the expression and function of indoleamine-2,3-dioxygenase in mesenchymal stromal cells. J R Soc Interface. 2020;17:20190815 pubmed publisher
Hsu J, Bai M, Li K, Yang J, Chu N, Cole P, et al. The protein kinase Akt acts as a coat adaptor in endocytic recycling. Nat Cell Biol. 2020;22:927-933 pubmed publisher
Tran B, Flanagan D, Ebert G, Warner N, Tran H, Fifis T, et al. The Hepatitis B Virus Pre-Core Protein p22 Activates Wnt Signaling. Cancers (Basel). 2020;12: pubmed publisher
Liao K, Niu F, Hu G, Guo M, Sil S, Buch S. HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells. Tissue Barriers. 2020;:1748983 pubmed publisher
Poston R, Murphy L, Rejepova A, Ghaninejad Esfahani M, Segales J, Mulligan K, et al. Certain ortho-hydroxylated brominated ethers are promiscuous kinase inhibitors that impair neuronal signaling and neurodevelopmental processes. J Biol Chem. 2020;295:6120-6137 pubmed publisher
Patrício M, Cox C, Blue C, Barnard A, Martinez Fernandez de la Camara C, MacLaren R. Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy. Mol Ther Methods Clin Dev. 2020;17:99-106 pubmed publisher
Kim Y, Gupta Vallur P, Jones V, Worley B, Shimko S, Shin D, et al. Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells. Oncogene. 2020;39:1619-1633 pubmed publisher
Salerno A, Rentz T, Dorighello G, Marques A, Lorza Gil E, Wanschel A, et al. Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice. Biochem J. 2019;476:3769-3789 pubmed publisher
Jeong S, Hogarth P, Placzek A, Gregory A, Fox R, Zhen D, et al. 4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN. EMBO Mol Med. 2019;11:e10489 pubmed publisher
Davidge B, Rebola K, Agbor L, Sigmund C, Singer J. Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E. J Cell Sci. 2019;132: pubmed publisher
Yang J, Hsu J, Park S, Lee S, Li J, Bai M, et al. ALDH7A1 inhibits the intracellular transport pathways during hypoxia and starvation to promote cellular energy homeostasis. Nat Commun. 2019;10:4068 pubmed publisher
Youseff B, Brewer T, McNally K, Izuogu A, Lubick K, Presloid J, et al. TRAF6 Plays a Proviral Role in Tick-Borne Flavivirus Infection through Interaction with the NS3 Protease. iScience. 2019;15:489-501 pubmed publisher
Puranik N, Srivastava P, Bhatt G, John Mary D, Limaye A, Sivaraman J. Determination and analysis of agonist and antagonist potential of naturally occurring flavonoids for estrogen receptor (ERα) by various parameters and molecular modelling approach. Sci Rep. 2019;9:7450 pubmed publisher
Casas Grajales S, Ramos Tovar E, Chávez Estrada E, Alvarez Suarez D, Hernández Aquino E, Reyes Gordillo K, et al. Antioxidant and immunomodulatory activity induced by stevioside in liver damage: In vivo, in vitro and in silico assays. Life Sci. 2019;224:187-196 pubmed publisher
Rana N, Singh P, Koch B. CoCl2 simulated hypoxia induce cell proliferation and alter the expression pattern of hypoxia associated genes involved in angiogenesis and apoptosis. Biol Res. 2019;52:12 pubmed publisher
Sharma S, Wang J, Alqassim E, Portwood S, Cortes Gomez E, Maguire O, et al. Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells. Genome Biol. 2019;20:37 pubmed publisher
Fragniere A, Stott S, Fazal S, Andreasen M, Scott K, Barker R. Hyperosmotic stress induces cell-dependent aggregation of α-synuclein. Sci Rep. 2019;9:2288 pubmed publisher
Lee J, Lee D, Park J, Han J. Sodium nitrite-derived nitric oxide protects rat testes against ischemia/reperfusion injury. Asian J Androl. 2018;: pubmed publisher
Medina Cano D, Ucuncu E, Nguyen L, Nicouleau M, Lipecka J, Bizot J, et al. High N-glycan multiplicity is critical for neuronal adhesion and sensitizes the developing cerebellum to N-glycosylation defect. elife. 2018;7: pubmed publisher
Bayrer J, Wang H, Nattiv R, Suzawa M, Escusa H, Fletterick R, et al. LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nat Commun. 2018;9:4055 pubmed publisher
Kantor B, Tagliafierro L, Gu J, Zamora M, Ilich E, Grenier C, et al. Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD. Mol Ther. 2018;26:2638-2649 pubmed publisher
Yang J, Hsu J, Park S, Li J, Oldham W, Beznoussenko G, et al. GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis. Nature. 2018;561:263-267 pubmed publisher
Lee F, Zhang H, Jiang A, Zai C, Liu F. Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis. Sci Rep. 2018;8:12856 pubmed publisher
Akiyama H, Miller C, Ettinger C, Belkina A, Snyder Cappione J, Gummuluru S. HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction. Nat Commun. 2018;9:3450 pubmed publisher
Ramkumar N, Stuart D, Abraham N, Kohan D. Nephron prorenin receptor deficiency alters renal medullary endothelin-1 and endothelin receptor expression. Physiol Res. 2018;67:S127-S136 pubmed
Shao W, Earley L, Chai Z, Chen X, Sun J, He T, et al. Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction. JCI Insight. 2018;3: pubmed publisher
Ramos Tovar E, Hernández Aquino E, Casas Grajales S, Buendia Montaño L, Galindo Gómez S, Camacho J, et al. Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation. Oxid Med Cell Longev. 2018;2018:3823426 pubmed publisher
Poston R, Dunn C, Sarkar P, Saha R. Persistent 6-OH-BDE-47 exposure impairs functional neuronal maturation and alters expression of neurodevelopmentally-relevant chromatin remodelers. Environ Epigenet. 2018;4:dvx020 pubmed publisher
Patrício M, Barnard A, Cox C, Blue C, MacLaren R. The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A. Mol Ther Methods Clin Dev. 2018;9:288-295 pubmed publisher
Gludovacz E, Maresch D, Lopes de Carvalho L, Puxbaum V, Baier L, Sützl L, et al. Oligomannosidic glycans at Asn-110 are essential for secretion of human diamine oxidase. J Biol Chem. 2018;293:1070-1087 pubmed publisher
Zhang P, He D, Xu Y, Hou J, Pan B, Wang Y, et al. Genome-wide identification and differential analysis of translational initiation. Nat Commun. 2017;8:1749 pubmed publisher
Bajikar S, Wang C, Borten M, Pereira E, Atkins K, Janes K. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Dev Cell. 2017;43:418-435.e13 pubmed publisher
Wozniak D, Kajdacsy Balla A, Macias V, Ball Kell S, Zenner M, Bie W, et al. PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer. Nat Commun. 2017;8:1508 pubmed publisher
Mitkevich V, Burnysheva K, Petrushanko I, Adzhubei A, Schulga A, Chumakov P, et al. Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins. Oncotarget. 2017;8:72666-72675 pubmed publisher
Dunn C, Sarkar P, Bailey E, Farris S, Zhao M, Ward J, et al. Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes. Eneuro. 2017;4: pubmed publisher
Emery C, Monaco K, Wang P, Balak M, Freeman A, Meltzer J, et al. BRAF-inhibitor Associated MEK Mutations Increase RAF-Dependent and -Independent Enzymatic Activity. Mol Cancer Res. 2017;15:1431-1444 pubmed publisher
Miosge L, Sontani Y, Chuah A, Horikawa K, Russell T, Mei Y, et al. Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion. Proc Natl Acad Sci U S A. 2017;114:E5216-E5225 pubmed publisher
Fischer M, McClements M, Martinez Fernandez de la Camara C, Bellingrath J, Dauletbekov D, Ramsden S, et al. Codon-Optimized RPGR Improves Stability and Efficacy of AAV8 Gene Therapy in Two Mouse Models of X-Linked Retinitis Pigmentosa. Mol Ther. 2017;25:1854-1865 pubmed publisher
Vicente Miranda H, Szego E, Oliveira L, Breda C, Darendelioglu E, de Oliveira R, et al. Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies. Brain. 2017;140:1399-1419 pubmed publisher
Lakunina V, Burnysheva K, Mitkevich V, Makarov A, Petrushanko I. [Changes in the receptor function of Na,K-ATPase during hypoxia and ischemia]. Mol Biol (Mosk). 2017;51:172-179 pubmed publisher
Sharma S, Wang J, Cortes Gomez E, TAGGART R, Baysal B. Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes. Hum Mol Genet. 2017;26:1328-1339 pubmed publisher
Sharma S, Patnaik S, TAGGART R, Baysal B. The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme. Sci Rep. 2016;6:39100 pubmed publisher
Vicente Miranda H, Gomes M, Branco Santos J, Breda C, Lázaro D, Lopes L, et al. Glycation potentiates neurodegeneration in models of Huntington's disease. Sci Rep. 2016;6:36798 pubmed publisher
Grootaert M, Schrijvers D, Hermans M, Van Hoof V, De Meyer G, Martinet W. Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice. Oxid Med Cell Longev. 2016;2016:3087469 pubmed
Horn T, Ferretti S, Ebel N, Tam A, Ho S, Harbinski F, et al. High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells. Cancer Res. 2016;76:6950-6963 pubmed
Moore J, Zhao J, Keith M, Amraotkar A, Wysoczynski M, Hong K, et al. The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism. Stem Cells. 2016;34:2916-2929 pubmed publisher
Merry C, McMahon S, Forrest M, Bartels C, Saiakhova A, Bartel C, et al. Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer. Oncotarget. 2016;7:53230-53244 pubmed publisher
Manjegowda M, Gupta P, Limaye A. Validation data of a rabbit antiserum and affinity purified polyclonal antibody against the N-terminus of human GPR30. Data Brief. 2016;7:1015-20 pubmed publisher
Sharma S, Patnaik S, Kemer Z, Baysal B. Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes. RNA Biol. 2017;14:603-610 pubmed publisher
Rutering J, Ilmer M, Recio A, Coleman M, Vykoukal J, Alt E. Improved Method for Isolation of Neonatal Rat Cardiomyocytes with Increased Yield of C-Kit+ Cardiac Progenitor Cells. J Stem Cell Res Ther. 2015;5:1-8 pubmed
Kang J, Dervan P. A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma. Q Rev Biophys. 2015;48:453-64 pubmed publisher
Sharma S, Patnaik S, Taggart R, Kannisto E, Enriquez S, Gollnick P, et al. APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages. Nat Commun. 2015;6:6881 pubmed publisher
Lechuga T, Zhang H, Sheibani L, Karim M, Jia J, Magness R, et al. Estrogen Replacement Therapy in Ovariectomized Nonpregnant Ewes Stimulates Uterine Artery Hydrogen Sulfide Biosynthesis by Selectively Up-Regulating Cystathionine β-Synthase Expression. Endocrinology. 2015;156:2288-98 pubmed publisher
Merry C, McMahon S, Thompson C, Miskimen K, Harris L, Khalil A. Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer. Breast Cancer Res Treat. 2015;150:321-34 pubmed publisher
Franchini A, Hunt D, Melendez J, Drake J. FcγR-driven release of IL-6 by macrophages requires NOX2-dependent production of reactive oxygen species. J Biol Chem. 2013;288:25098-108 pubmed publisher
Incontro S, Ciruela F, ZIFF E, Hofmann F, Sánchez Prieto J, Torres M. The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells. Biochim Biophys Acta. 2013;1833:1820-31 pubmed publisher
Cottarel J, Frit P, Bombarde O, Salles B, Négrel A, Bernard S, et al. A noncatalytic function of the ligation complex during nonhomologous end joining. J Cell Biol. 2013;200:173-86 pubmed publisher
Park M, Chu F, Xie J, Wang Y, Bhattacharya P, Chan W. Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40. Anal Biochem. 2011;410:257-65 pubmed publisher
Kuhr F, Zhang Y, Brovkovych V, Skidgel R. Beta-arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase. FASEB J. 2010;24:2475-83 pubmed publisher
product information
Product Type :
Antibody
Product Name :
beta Actin Monoclonal Antibody (AC-15)
Catalog # :
AM4302
Quantity :
100 µg
Price :
US 306
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Bovine, Canine, Chicken, Drosophila, Feline, Guinea Pig, Human, Ovine, Porcine, Rabbit
Applications :
Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Bovine, Canine, Chicken, Drosophila, Feline, Guinea Pig, Human, Ovine, Porcine, Rabbit
Clone :
AC-15
Isotype :
IgG1
Storage :
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Description :
Beta actin is one of six actin isoforms which have been identified. Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.
Immunogen :
A slightly modified synthetic beta-cytoplasmic actin N-terminal peptide,Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
0610041G09Rik; AA959943; AAT6; ACT; Act4; Act-4; ACT-5; ACTA; acta1; acta1b; ACTA2; Acta-2; ACTA3; actb; actb.L; actb1; actba; ACTC; actc1; Actc-1; actc1b; ACTE; Actg; ACTG1; Actg2; ACTGE; actin; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 1, skeletal muscle b; actin alpha 2, smooth muscle; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin alpha cardiac muscle 1b; actin beta; actin gamma 1; actin gamma 2, smooth muscle; actin, alpha 1, skeletal muscle; actin, alpha 1b, skeletal muscle; actin, alpha 2, smooth muscle, aorta; Actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; actin, alpha cardiac muscle 1b; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; actin, beta; actin, beta 1; actin, beta L homeolog; actin, beta, cytoplasmic; actin, cytoplasmic 1; Actin, cytoplasmic 1, N-terminally processed; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; actin, gamma 1; actin, gamma 2, smooth muscle, enteric; actin, gamma, cytoplasmic 1; actin, gamma-enteric smooth muscle; Actin, gamma-enteric smooth muscle, intermediate form; actin-like protein; Actl; ACTL3; Acts; ACTSA; ACTSG; Actsk-1; Actvs; Actx; AL023024; alpha actin 1; alpha-actin cardiac; alpha-actin-1; Alpha-actin-2; alpha-actin-3; alphac-actin; Alpha-cardiac actin; alphaSMA; alpha-smooth muscle actin; ASD5; ASMA; a-SMA; Atcb; Bact; Bact; actin; B-actin; bactin1; bactin1 protein; bactzf; B-ACTZF; beta actin; beta cytoskeletal actin; beta-actin; beta-actin FE-3; beta-actin-1; BRWS1; BRWS2; Cap Z; capZ beta; cardiac muscle alpha actin 1; cardiofunk; cell growth-inhibiting gene 46 protein; Cfk; CFTD; CFTD1; CFTDM; CMD1R; CMH11; cytoplasmic 1; cytoplasmic beta-actin; cytoskeletal beta actin; cytoskeletal gamma-actin; cytoskeletal protein; cytoskeleton actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; DFNA20; DFNA26; E430023M04Rik; E51; epididymis luminal protein 176; fa27h01; fb83f06; gamma actin; gamma non-muscle actin; gamma-2-actin; Gamma-actin; gamma-enteric smooth muscle actin; GIG46; HEL-176; hm:zeh0631; I79_002310; I79_013242; I79_019066; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; PS1TP5-binding protein 1; PS1TP5BP1; SHPM; similar to beta actin; skeletal alpha actin; skeletal alpha1 actin; sma; SMalphaA; SMGA; smooth muscle alpha-actin; smooth muscle gamma-actin; vascular smooth muscle alpha-actin; VSCM; wu:fa27h01; wu:fb63d03; wu:fb83f06; wu:fd18f05; XELAEV_18045052mg; zeh0631
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA