4EBP1 Monoclonal Antibody (554R16) | Invitrogen AHO1382 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

4EBP1 Monoclonal Antibody (554R16)

catalog :

AHO1382

quantity :

100 ug

price :

US 520.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

554R16

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 2	Man N, Chen Y, Zheng F, Zhou W, Wen L. Induction of genuine autophagy by cationic lipids in mammalian cells. Autophagy. 2010;6:449-54 pubmed publisher
	Danese A, Patergnani S, Maresca A, Peron C, Raimondi A, Caporali L, et al. Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy. Cell Rep. 2022;40:111124 pubmed publisher
	Vahsen B, Ribas V, Sundermeyer J, Boecker A, Dambeck V, Lenz C, et al. Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. Cell Death Differ. 2020;27:2810-2827 pubmed publisher
	Papavassiliou K, Zoi I, Gargalionis A, Koutsilieris M. Polycystin-1 affects cancer cell behaviour and interacts with mTOR and Jak signalling pathways in cancer cell lines. J Cell Mol Med. 2019;23:6215-6227 pubmed publisher
	Li B, Zhou C, Yi L, Xu L, Xu M. Effect and molecular mechanism of mTOR inhibitor rapamycin on temozolomide-induced autophagic death of U251 glioma cells. Oncol Lett. 2018;15:2477-2484 pubmed publisher
	Serpa J, Caiado F, Carvalho T, Torre C, Gonçalves L, Casalou C, et al. Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells. J Biol Chem. 2010;285:39211-23 pubmed publisher

product information

Product Type :

Antibody

Product Name :

4EBP1 Monoclonal Antibody (554R16)

Catalog # :

AHO1382

Quantity :

100 ug

Price :

US 520.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:250, Western Blot: 1:500

Species :

Human, Mouse, Rat

Clone :

554R16

Isotype :

IgG1, kappa

Storage :

-20 C

Description :

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Immunogen :

Recombinant human 4E-BP1 protein expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Western Blot: 1:500

Aliases :

4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

more info or order :

Invitrogen product webpage