mTOR Monoclonal Antibody (215Q18) | Invitrogen AHO1232 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

mTOR Monoclonal Antibody (215Q18)

catalog :

AHO1232

quantity :

100 µg

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

215Q18

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 6	Figueroa González G, García Castillo V, Coronel Hernández J, López Urrutia E, León Cabrera S, Arias Romero L, et al. Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer. J Cancer. 2016;7:1632-1644 pubmed
western blot; rat; 1:500	Sosanya N, Brager D, Wolfe S, Niere F, Raab Graham K. Rapamycin reveals an mTOR-independent repression of Kv1.1 expression during epileptogenesis. Neurobiol Dis. 2015;73:96-105 pubmed publisher
	Tarawneh N, Hamadneh L, Abu Irmaileh B, Shraideh Z, Bustanji Y, Abdalla S. Berberine Inhibited Growth and Migration of Human Colon Cancer Cell Lines by Increasing Phosphatase and Tensin and Inhibiting Aquaporins 1, 3 and 5 Expressions. Molecules. 2023;28: pubmed publisher
	Harb I, Ashour H, Rashed L, Mostafa A, Samir M, Aboulhoda B, et al. Nicorandil mitigates amiodarone-induced pulmonary toxicity and fibrosis in association with the inhibition of lung TGF-β1/PI3K/Akt1-p/mTOR axis in rats. Clin Exp Pharmacol Physiol. 2023;50:96-106 pubmed publisher
	Castro B, de Paz N, Gonz xe1 lez S, Rodr xed guez Luna A. SCA® Slows the Decline of Functional Parameters Associated with Senescence in Skin Cells. Int J Mol Sci. 2022;23: pubmed publisher
	Rashid M, Ali R, Almuzzaini B, Song H, Alhallaj A, Abdulkarim A, et al. Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer. Cancer Med. 2021;10:8138-8150 pubmed publisher
	Ali R, Al Zahrani H, Barhoumi T, Alhallaj A, Mashhour A, Alshammari M, et al. Isolation and Establishment of a Highly Proliferative, Cancer Stem Cell-Like, and Naturally Immortalized Triple-Negative Breast Cancer Cell Line, KAIMRC2. Cells. 2021;10: pubmed publisher
	Xu M, Gu M, Zhou J, Da J, Wang Z. Interaction of YAP1 and mTOR promotes bladder cancer progression. Int J Oncol. 2020;56:232-242 pubmed publisher
	Notaras M, Allen M, Longo F, Volk N, Toth M, Li Jeon N, et al. UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function. Mol Psychiatry. 2019;: pubmed publisher
	Kälin S, Becker M, Ott V, Serr I, Hosp F, Mollah M, et al. A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function. Cell Metab. 2017;26:475-492.e7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

mTOR Monoclonal Antibody (215Q18)

Catalog # :

AHO1232

Quantity :

100 µg

Price :

US 450.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay-dependent

Species :

Human, Mouse, Rat

Clone :

215Q18

Isotype :

IgG2b, kappa

Storage :

-20°C

Description :

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.

Immunogen :

Recombinant fragment of human mTOR expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay-dependent

Aliases :

2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS

more info or order :

Invitrogen product webpage