STAT1 Monoclonal Antibody (STAT1-79) | Invitrogen AHO0832 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

STAT1 Monoclonal Antibody (STAT1-79)

catalog :

AHO0832

quantity :

100 µg

price :

US 500.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

STAT1-79

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4d	Stav Noraas T, Edelmann R, Poulsen L, Sundnes O, Phung D, Küchler A, et al. Endothelial IL-33 Expression Is Augmented by Adenoviral Activation of the DNA Damage Machinery. J Immunol. 2017;198:3318-3325 pubmed publisher
	Geiller B, Greigert V, Hillenbrand C, Gommenginger C, Beal L, Brunet J, et al. Type I and III interferons shape the retinal cytokine network and barrier function in an in vitro model of ocular toxoplasmosis. Front Immunol. 2023;14:1148037 pubmed publisher
	Kim D, Tu K, Wei A, Lau A, Gonzalez Gil A, Cao T, et al. Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes. Mol Neurodegener. 2022;17:83 pubmed publisher
	Zhang Y, Gargan S, Roche F, Frieman M, Stevenson N. Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells. Viruses. 2022;14: pubmed publisher
	Vecchio E, Caiazza C, Mimmi S, Avagliano A, Iaccino E, Brusco T, et al. Metabolites Profiling of Melanoma Interstitial Fluids Reveals Uridine Diphosphate as Potent Immune Modulator Capable of Limiting Tumor Growth. Front Cell Dev Biol. 2021;9:730726 pubmed publisher
	Shemesh M, Aktepe T, Deerain J, McAuley J, Audsley M, David C, et al. SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon. PLoS Pathog. 2021;17:e1009800 pubmed publisher
	Fu B, Lin X, Tan S, Zhang R, Xue W, Zhang H, et al. MiR-342 controls Mycobacterium tuberculosis susceptibility by modulating inflammation and cell death. EMBO Rep. 2021;22:e52252 pubmed publisher
	Fu B, Yin S, Lin X, Shi L, Wang Y, Zhang S, et al. PTPN14 aggravates inflammation through promoting proteasomal degradation of SOCS7 in acute liver failure. Cell Death Dis. 2020;11:803 pubmed publisher
	Wu S, Wu Y, Lu Y, Yue Y, Cui C, Yu M, et al. STAT1 expression and HPV16 viral load predict cervical lesion progression. Oncol Lett. 2020;20:28 pubmed publisher
	Fu B, Xue W, Zhang H, Zhang R, Feldman K, Zhao Q, et al. MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling. MBio. 2020;11: pubmed publisher
	Clarke M, Mackay A, Ismer B, Pickles J, Tatevossian R, Newman S, et al. Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes. Cancer Discov. 2020;10:942-963 pubmed publisher
	Hu Y, Kang C, Zhao J, Nie Y, Zheng L, Li H, et al. LncRNA PLAC2 down-regulates RPL36 expression and blocks cell cycle progression in glioma through a mechanism involving STAT1. J Cell Mol Med. 2018;22:497-510 pubmed publisher
	Yu J, Li X, Wang Y, Li B, Li H, Li Y, et al. PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1. PLoS ONE. 2011;6:e19511 pubmed publisher

product information

Product Type :

Antibody

Product Name :

STAT1 Monoclonal Antibody (STAT1-79)

Catalog # :

AHO0832

Quantity :

100 µg

Price :

US 500.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ChIP Assay: 5 µL, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 0.5-1 µg/mL, Western Blot: 1:500

Species :

Human, Mouse, Rat

Clone :

STAT1-79

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors. STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6. STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2. STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes. Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.

Immunogen :

Recombinant human STAT1-alpha expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 5 µL, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 0.5-1 µg/mL, Western Blot: 1:500

Aliases :

2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84

more info or order :

Invitrogen product webpage