GRB2 Monoclonal Antibody (2GB04 (C1.4)) | Invitrogen AHO0522 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GRB2 Monoclonal Antibody (2GB04 (C1.4))

catalog :

AHO0522

quantity :

500 µL

price :

US 385

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2GB04 (C1.4)

reactivity :

human, mouse, rat, bovine, Xenopus laevis

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Jang I, Cronshaw D, Xie L, Fang G, Zhang J, Oh H, et al. Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction. Proc Natl Acad Sci U S A. 2011;108:7926-31 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GRB2 Monoclonal Antibody (2GB04 (C1.4))

Catalog # :

AHO0522

Quantity :

500 µL

Price :

US 385

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Bovine, Human, Mouse, Rat, Xenopus laevis

Applications :

Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): Assay-Dependent

Species :

Bovine, Human, Mouse, Rat, Xenopus laevis

Clone :

2GB04 (C1.4)

Isotype :

IgG1, kappa

Storage :

4° C

Description :

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.

Immunogen :

Purified recombinant human Grb2 protein.

Format :

Liquid

Applications w/Dilutions :

Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): Assay-Dependent

Aliases :

AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; Ash; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; Grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; Protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg