This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Fyn Monoclonal Antibody (1S)
catalog :
AHO0482
quantity :
500 µL
price :
US 456.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1S
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 9
Reference
Vernot J, Perdomo Arciniegas A, Pérez Quintero L, Martínez D. Modulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri. J Immunol Res. 2015;2015:395371 pubmed publisher
Boggs J, Homchaudhuri L, Ranagaraj G, Liu Y, Smith G, Harauz G. Interaction of myelin basic protein with cytoskeletal and signaling proteins in cultured primary oligodendrocytes and N19 oligodendroglial cells. BMC Res Notes. 2014;7:387 pubmed publisher
Honda K, Sakaguchi T, Sakai K, Schmedt C, Ramirez A, Jorcano J, et al. Epidermal hyperplasia and papillomatosis in mice with a keratinocyte-restricted deletion of csk. Carcinogenesis. 2007;28:2074-81 pubmed
Qian J, Niu J, Li M, Chiao P, Tsao M. In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Res. 2005;65:5045-53 pubmed
Chen M, Wang Y, Liu Y, Hou X, Zhang Q, Meng F, et al. Possible mechanisms underlying the protective effects of SY-21, an extract of a traditional Chinese herb, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampus. Brain Res. 2003;989:180-6 pubmed
Hou X, Zhang G, Yan J, Liu Y. Increased tyrosine phosphorylation of alpha(1C) subunits of L-type voltage-gated calcium channels and interactions among Src/Fyn, PSD-95 and alpha(1C) in rat hippocampus after transient brain ischemia. Brain Res. 2003;979:43-50 pubmed
Hou X, Zhang G, Zong Y. Suppression of postsynaptic density protein 95 expression attenuates increased tyrosine phosphorylation of NR2A subunits of N-methyl-D-aspartate receptors and interactions of Src and Fyn with NR2A after transient brain ischemia in rat hippocampus. Neurosci Lett. 2003;343:125-8 pubmed
Chen M, Hou X, Zhang G. Tyrosine kinase and tyrosine phosphatase participate in regulation of interactions of NMDA receptor subunit 2A with Src and Fyn mediated by PSD-95 after transient brain ischemia. Neurosci Lett. 2003;339:29-32 pubmed
Hou X, Zhang G, Yan J, Chen M, Liu Y. Activation of NMDA receptors and L-type voltage-gated calcium channels mediates enhanced formation of Fyn-PSD95-NR2A complex after transient brain ischemia. Brain Res. 2002;955:123-32 pubmed
product information
Product Type :
Antibody
Product Name :
Fyn Monoclonal Antibody (1S)
Catalog # :
AHO0482
Quantity :
500 µL
Price :
US 456.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 8-15 µg, Western Blot: 1-3 µg/mL
Species :
Human, Mouse, Rat
Clone :
1S
Isotype :
IgG1, kappa
Storage :
4° C
Description :
FYN is a SRC-related kinase expressed in brain, skeletal muscle and adipose tissues. Fyn functions in a large number of pathways and has been shown to play a role in memory. FYN is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Immunogen :
Recombinant protein corresponding to amino acid residues 1-206 of murine p59fynprotein.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 8-15 µg, Western Blot: 1-3 µg/mL
Aliases :
AI448320; AW552119; C syn protooncogene; c-syn protooncogene; EC 2.7.10.2; Fyn; fyn {ECO:0000312; FYN oncogene related to SRC, FGR, YES; Fyn proto-oncogene; FYN proto-oncogene, Src family tyrosine kinase; kinase Fyn; MGC45350; OKT3-induced calcium influx regulator; OTTHUMP00000017916; OTTHUMP00000017917; P59 p59-Fyn; p59-Fyn; Proto-oncogene c-Fyn; Protooncogene Syn; proto-oncogene Syn; proto-oncogene tyrosine-protein kinase Fyn; RGD:2641}; RP1-66H14.1; SLK; Src Kinase p59; Src like kinase; src/yes-related novel; src-like kinase; SYN; tyrosine kinase p59fyn(T); tyrosine-protein kinase Fyn
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA