IL-6 Monoclonal Antibody (677B6A2) | Invitrogen AHC0562 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-6 Monoclonal Antibody (677B6A2)

catalog :

AHC0562

quantity :

500 µg

price :

US 446.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

677B6A2

reactivity :

human

application :

ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
ELISA; human; 1:2000; fig 6d	Rodriguez E, Boelaars K, Brown K, Madunić K, van Ee T, Dijk F, et al. Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits. Commun Biol. 2022;5:41 pubmed publisher
immunocytochemistry; human ELISA; human	de Thier P, Bacharouche J, Duval J, Skali Lami S, Francius G. Atomic force microscopy analysis of IgG films at hydrophobic surfaces: a promising method to probe IgG orientations and optimize ELISA tests performance. Biochim Biophys Acta. 2015;1854:138-45 pubmed publisher
ELISA; human; fig 1	Bartels E, Falbe Wätjen I, Littrup Andersen E, Danneskiold Samsøe B, Bliddal H, Ribel Madsen S. Rheumatoid factor and its interference with cytokine measurements: problems and solutions. Arthritis. 2011;2011:741071 pubmed publisher
immunocytochemistry; human; 1:10; fig 3	Munster B, Aronica E, Zwinderman A, Eikelenboom P, Cunningham C, Rooij S. Neuroinflammation in delirium: a postmortem case-control study. Rejuvenation Res. 2011;14:615-22 pubmed publisher
ELISA; human; fig 6	BORCHERDING D, Hugo E, Idelman G, De Silva A, Richtand N, Loftus J, et al. Dopamine receptors in human adipocytes: expression and functions. PLoS ONE. 2011;6:e25537 pubmed publisher
ELISA; human; fig 1	LaPensee C, Hugo E, Ben Jonathan N. Insulin stimulates interleukin-6 expression and release in LS14 human adipocytes through multiple signaling pathways. Endocrinology. 2008;149:5415-22 pubmed publisher
immunoprecipitation; human	Graber J, Allie S, Mullen K, Jones M, Wang T, Krishnan C, et al. Interleukin-17 in transverse myelitis and multiple sclerosis. J Neuroimmunol. 2008;196:124-32 pubmed publisher
immunohistochemistry - paraffin section; human; 20 ug/ml	van Heteren J, Rozenberg F, Aronica E, Troost D, Lebon P, Kuijpers T. Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome. Glia. 2008;56:568-78 pubmed publisher
ELISA; human	Denis M, Reenaers C, Fontaine F, Belaiche J, Louis E. Assessment of endoscopic activity index and biological inflammatory markers in clinically active Crohn's disease with normal C-reactive protein serum level. Inflamm Bowel Dis. 2007;13:1100-5 pubmed
ELISA; human; fig 3	Takeda K, Suzuki T, Shimada S, Shida K, Nanno M, Okumura K. Interleukin-12 is involved in the enhancement of human natural killer cell activity by Lactobacillus casei Shirota. Clin Exp Immunol. 2006;146:109-15 pubmed
ELISA; human	Janke M, Witsch E, Mages H, Hutloff A, Kroczek R. Eminent role of ICOS costimulation for T cells interacting with plasmacytoid dendritic cells. Immunology. 2006;118:353-60 pubmed
ELISA; human	Kooijman R, Coppens A, Hooghe Peters E. Igf-I inhibits spontaneous apoptosis in human granulocytes. Endocrinology. 2002;143:1206-12 pubmed
	Kesavalu L, Falk C, Davis K, Steffen M, Xu X, Holt S, et al. Biological characterization of lipopolysaccharide from Treponema pectinovorum. Infect Immun. 2002;70:211-7 pubmed
	Nixon C, Steffen M, Ebersole J. Cytokine responses to treponema pectinovorum and treponema denticola in human gingival fibroblasts. Infect Immun. 2000;68:5284-92 pubmed

product information

Product Type :

Antibody

Product Name :

IL-6 Monoclonal Antibody (677B6A2)

Catalog # :

AHC0562

Quantity :

500 µg

Price :

US 446.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent

Species :

Human

Clone :

677B6A2

Isotype :

IgG1, kappa

Storage :

4° C

Description :

IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.

Immunogen :

Recombinant human IL-6.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6

more info or order :

Invitrogen product webpage