IL-13 Monoclonal Antibody (JES10-5A2) | Invitrogen AHC0132 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-13 Monoclonal Antibody (JES10-5A2)

catalog :

AHC0132

quantity :

500 µg

price :

US 418.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

JES10-5A2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; tbl 2	Koscher V, Milhe F, El Biaze M, Vervloet D, Magnan A. Variation of T-cell activation in allergic subjects during natural pollen exposure. Allergy. 2006;61:35-42 pubmed
immunocytochemistry; human	Boniface S, Koscher V, Mamessier E, El Biaze M, Dupuy P, Lorec A, et al. Assessment of T lymphocyte cytokine production in induced sputum from asthmatics: a flow cytometry study. Clin Exp Allergy. 2003;33:1238-43 pubmed
	Kvorjak M, Ahmed Y, Miller M, Sriram R, Coronnello C, Hashash J, et al. Cross-talk between Colon Cells and Macrophages Increases ST6GALNAC1 and MUC1-sTn Expression in Ulcerative Colitis and Colitis-Associated Colon Cancer. Cancer Immunol Res. 2020;8:167-178 pubmed publisher
	Khalmuratova R, Shin H, Kim D, Park J. Interleukin (IL)-13 and IL-17A contribute to neo-osteogenesis in chronic rhinosinusitis by inducing RUNX2. EBioMedicine. 2019;46:330-341 pubmed publisher
	Vargas Hernandez A, Mace E, Zimmerman O, Zerbe C, Freeman A, Rosenzweig S, et al. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations. J Allergy Clin Immunol. 2018;141:2142-2155.e5 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL-13 Monoclonal Antibody (JES10-5A2)

Catalog # :

AHC0132

Quantity :

500 µg

Price :

US 418.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rat

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunohistochemistry: Assay-dependent, Neutralization: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

JES10-5A2

Isotype :

IgG1

Storage :

-20°C

Description :

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

Immunogen :

Purified recombinant human IL-13

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunohistochemistry: Assay-dependent, Neutralization: Assay-dependent, Western Blot: Assay-dependent

Aliases :

ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600

more info or order :

Invitrogen product webpage