| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; 1:1000; loading ...; fig 4b
| Van Hummel A, Bi M, Ippati S, van der Hoven J, Volkerling A, Lee W, et al. No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice. PLoS ONE. 2016;11:e0163236 pubmed publisher |
- immunocytochemistry; human; fig 3
- immunocytochemistry knockout validation; mouse; fig 3
| Mansuroglu Z, Benhelli Mokrani H, Marcato V, Sultan A, Violet M, Chauderlier A, et al. Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin. Sci Rep. 2016;6:33047 pubmed publisher |
- immunocytochemistry; human; 1:200; loading ...; fig 3e
- western blot; human; 1:1000; loading ...; fig s2
- immunocytochemistry; mouse; 1:500; loading ...; fig 1a
| Easton A, Jensen M, Wang C, Hagedorn P, Li Y, WEED M, et al. Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies. Mol Ther Nucleic Acids. 2022;29:625-642 pubmed publisher |
- western blot; rat; 1:500; loading ...; fig 2f
| Guix F, Capitán A, Casadomé Perales Á, Palomares Perez I, López Del Castillo I, Miguel V, et al. Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup. Life Sci Alliance. 2021;4: pubmed publisher |
- immunocytochemistry; human; 0.5 ug/ml; loading ...; fig 6d
| Sokratian A, Ziaee J, Kelly K, Chang A, Bryant N, Wang S, et al. Heterogeneity in α-synuclein fibril activity correlates to disease phenotypes in Lewy body dementia. Acta Neuropathol. 2021;141:547-564 pubmed publisher |
- immunocytochemistry; mouse; 1:200; loading ...; fig 1a
| Choi G, Lee H, Chae C, Cho J, Jung Y, Kim J, et al. BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects. Nat Commun. 2021;12:487 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2a
| Silva M, Nandi G, Tentarelli S, Gurrell I, Jamier T, Lucente D, et al. Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons. Nat Commun. 2020;11:3258 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 3a
| Wander C, Tseng J, Song S, Al Housseiny H, Tart D, Ajit A, et al. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging. iScience. 2020;23:101255 pubmed publisher |
- western blot; human; 1:1000; loading ...
| Silva M, Ferguson F, Cai Q, Donovan K, Nandi G, Patnaik D, et al. Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. elife. 2019;8: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 1c
| Merezhko M, Brunello C, Yan X, Vihinen H, Jokitalo E, Uronen R, et al. Secretion of Tau via an Unconventional Non-vesicular Mechanism. Cell Rep. 2018;25:2027-2035.e4 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 8b
| Quaranta V, Rainer C, Nielsen S, Raymant M, Ahmed M, Engle D, et al. Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer. Cancer Res. 2018;78:4253-4269 pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 1a
| Tseng J, Xie L, Song S, Xie Y, Allen L, Ajit D, et al. The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. Cell Rep. 2017;20:2169-2183 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 2A
| Chen S, Sun J, Zhao G, Guo A, Chen Y, Fu R, et al. Liraglutide Improves Water Maze Learning and Memory Performance While Reduces Hyperphosphorylation of Tau and Neurofilaments in APP/PS1/Tau Triple Transgenic Mice. Neurochem Res. 2017;42:2326-2335 pubmed publisher |
- western blot; mouse; loading ...; fig 5a
| Maphis N, Jiang S, Binder J, Wright C, Gopalan B, Lamb B, et al. Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology. Front Mol Neurosci. 2017;10:69 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2e
| Li Y, Li Z, Jin T, Wang Z, Zhao P. Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits the Formation of Perineuronal Nets by Regulating the Expression and the Distribution of Hyaluronic Acid Synthases. J Alzheimers Dis. 2017;57:395-409 pubmed publisher |
- western blot; mouse; 1:5000; loading ...; fig 4b
| Shin S, Kim J, Lee J, Son Y, Lee M, Kim H, et al. Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro. Exp Mol Med. 2017;49:e287 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 7a
| Takahashi H, Klein Z, Bhagat S, Kaufman A, Kostylev M, Ikezu T, et al. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Acta Neuropathol. 2017;133:785-807 pubmed publisher |
- immunocytochemistry; rat; 1:1000; loading ...; fig s1a
| Soo Hoo L, Banna C, Radeke C, Sharma N, Albertolle M, Low S, et al. The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. PLoS ONE. 2016;11:e0163671 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Yoshitake J, Soeda Y, Ida T, Sumioka A, Yoshikawa M, Matsushita K, et al. Modification of Tau by 8-Nitroguanosine 3',5'-Cyclic Monophosphate (8-Nitro-cGMP): EFFECTS OF NITRIC OXIDE-LINKED CHEMICAL MODIFICATION ON TAU AGGREGATION. J Biol Chem. 2016;291:22714-22720 pubmed |
- western blot; human; fig s3
| Sohn P, Tracy T, Son H, Zhou Y, Leite R, Miller B, et al. Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment. Mol Neurodegener. 2016;11:47 pubmed publisher |
- immunocytochemistry; human; 1:600; fig 4
- western blot; human; 1:1000; fig 2
| Yan X, Nykänen N, Brunello C, Haapasalo A, Hiltunen M, Uronen R, et al. FRMD4A-cytohesin signaling modulates the cellular release of tau. J Cell Sci. 2016;129:2003-15 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:500; tbl 1
- western blot; mouse; 1:500; tbl 1
| Krishnan V, White Z, McMahon C, Hodgetts S, Fitzgerald M, Shavlakadze T, et al. A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice. J Neuropathol Exp Neurol. 2016;75:464-78 pubmed publisher |
- western blot; human; fig 2
| Ortuno D, Carlisle H, Miller S. Does inactivation of USP14 enhance degradation of proteasomal substrates that are associated with neurodegenerative diseases?. F1000Res. 2016;5:137 pubmed publisher |
- western blot; human; 1:10,000; fig 3f
| Choi W, de Poot S, Lee J, Kim J, Han D, Kim Y, et al. Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. Nat Commun. 2016;7:10963 pubmed publisher |
- western blot; human; fig 1
| Urnukhsaikhan E, Cho H, Mishig Ochir T, Seo Y, Park J. Pulsed electromagnetic fields promote survival and neuronal differentiation of human BM-MSCs. Life Sci. 2016;151:130-138 pubmed publisher |
- western blot; mouse; 1:1000; tbl 1
- western blot; human; 1:1000; tbl 1
| Piedrahita D, Castro Álvarez J, Boudreau R, Villegas Lanau A, Kosik K, Gallego Gómez J, et al. β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice. Front Cell Neurosci. 2015;9:498 pubmed publisher |
- western blot; human; fig 3
| Kailainathan S, Piers T, Yi J, Choi S, Fahey M, Borger E, et al. Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF). Pharmacol Res. 2016;104:97-107 pubmed publisher |
- western blot; cat; 1:1000; fig 4
| Chambers J, Tokuda T, Uchida K, Ishii R, Tatebe H, Takahashi E, et al. The domestic cat as a natural animal model of Alzheimer's disease. Acta Neuropathol Commun. 2015;3:78 pubmed publisher |
- western blot; mouse; 1:5000; fig 5
| Gyoneva S, Kim D, Katsumoto A, Kokiko Cochran O, Lamb B, Ransohoff R. Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury. J Neuroinflammation. 2015;12:228 pubmed publisher |
- western blot; human; 1,000 ug/ml; fig 10
| Puvenna V, Engeler M, Banjara M, Brennan C, Schreiber P, Dadas A, et al. Is phosphorylated tau unique to chronic traumatic encephalopathy? Phosphorylated tau in epileptic brain and chronic traumatic encephalopathy. Brain Res. 2016;1630:225-40 pubmed publisher |
- immunoprecipitation; human; fig 1
- western blot; human; fig 1
| Min S, Chen X, Tracy T, Li Y, Zhou Y, Wang C, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med. 2015;21:1154-62 pubmed publisher |
| de Paula C, Santiago F, de Oliveira A, Oliveira F, Almeida M, Carrettiero D. The Co-chaperone BAG2 Mediates Cold-Induced Accumulation of Phosphorylated Tau in SH-SY5Y Cells. Cell Mol Neurobiol. 2016;36:593-602 pubmed publisher |
- western blot; rat; 1:1000
| Sun L, Ban T, Liu C, Chen Q, Wang X, Yan M, et al. Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation. J Neurochem. 2015;134:1139-51 pubmed publisher |
- western blot; human; 1:5000; fig 1
| Sheik Mohideen S, Yamasaki Y, Omata Y, Tsuda L, Yoshiike Y. Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies. Sci Rep. 2015;5:10821 pubmed publisher |
- western blot; mouse; fig 4
| Petrov D, Pedrós I, Artiach G, Sureda F, Barroso E, Pallas M, et al. High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents. Biochim Biophys Acta. 2015;1852:1687-99 pubmed publisher |
| De Zio D, Molinari F, Rizza S, Gatta L, Ciotti M, Salvatore A, et al. Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth. Cell Mol Life Sci. 2015;72:4173-91 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:500; fig 2
- western blot; human; 1:1000; fig 4
| Ohia Nwoko O, Montazari S, Lau Y, Eriksen J. Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice. Mol Neurodegener. 2014;9:54 pubmed publisher |
- western blot; mouse; fig 2
| Castro Alvarez J, Uribe Arias S, Kosik K, Cardona Gómez G. Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice. Front Aging Neurosci. 2014;6:243 pubmed publisher |
- western blot; mouse; 1:20,000
| Lee S, Xu G, Jay T, Bhatta S, Kim K, Jung S, et al. Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway. J Neurosci. 2014;34:12538-46 pubmed publisher |
- immunohistochemistry; mouse; 1:3000
| Gheyara A, Ponnusamy R, Djukic B, Craft R, Ho K, Guo W, et al. Tau reduction prevents disease in a mouse model of Dravet syndrome. Ann Neurol. 2014;76:443-56 pubmed publisher |
| Pedr s I, Petrov D, Allgaier M, Sureda F, Barroso E, Beas Zarate C, et al. Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease. Biochim Biophys Acta. 2014;1842:1556-66 pubmed publisher |
- western blot; mouse; 1:500
| Liu X, Zhou J, Abid M, Yan H, Huang H, Wan L, et al. Berberine attenuates axonal transport impairment and axonopathy induced by Calyculin A in N2a cells. PLoS ONE. 2014;9:e93974 pubmed publisher |
- western blot; mouse; 1:1000
| Liu C, Götz J. Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus. PLoS ONE. 2013;8:e84849 pubmed publisher |
- western blot; mouse; 1:4000
| Notter T, Panzanelli P, PFISTER S, Mircsof D, Fritschy J. A protocol for concurrent high-quality immunohistochemical and biochemical analyses in adult mouse central nervous system. Eur J Neurosci. 2014;39:165-75 pubmed publisher |
- immunohistochemistry - frozen section; mouse
| Manich G, del Valle J, Cabezón I, Camins A, Pallas M, Pelegri C, et al. Presence of a neo-epitope and absence of amyloid beta and tau protein in degenerative hippocampal granules of aged mice. Age (Dordr). 2014;36:151-65 pubmed publisher |
- western blot; mouse; fig 6
| Ordóñez Gutiérrez L, Torres J, Gavin R, Anton M, Arroba Espinosa A, Espinosa J, et al. Cellular prion protein modulates ?-amyloid deposition in aged APP/PS1 transgenic mice. Neurobiol Aging. 2013;34:2793-804 pubmed publisher |
- immunohistochemistry; human; 1:1000
- western blot; human; 1:1000; fig 3
| Hebron M, Algarzae N, Lonskaya I, Moussa C. Fractalkine signaling and Tau hyper-phosphorylation are associated with autophagic alterations in lentiviral Tau and A?1-42 gene transfer models. Exp Neurol. 2014;251:127-38 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Porquet D, Casadesus G, Bayod S, Vicente A, Canudas A, Vilaplana J, et al. Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8. Age (Dordr). 2013;35:1851-65 pubmed publisher |
- western blot; mouse; fig 3
| Tian M, Zhu D, Xie W, Shi J. Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains. FEBS Lett. 2012;586:3737-45 pubmed publisher |
- immunohistochemistry; rat; 1:2000
| Karlsson O, Berg A, Lindström A, Hanrieder J, Arnerup G, Roman E, et al. Neonatal exposure to the cyanobacterial toxin BMAA induces changes in protein expression and neurodegeneration in adult hippocampus. Toxicol Sci. 2012;130:391-404 pubmed publisher |
- western blot; mouse; fig 1
| Sontag J, Nunbhakdi Craig V, White C, Halpain S, Sontag E. The protein phosphatase PP2A/B? binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies. J Biol Chem. 2012;287:14984-93 pubmed publisher |
- immunohistochemistry; mouse; fig 3
| Kaul T, Credle J, Haggerty T, Oaks A, Masliah E, Sidhu A. Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease. BMC Neurosci. 2011;12:79 pubmed publisher |
- western blot; human; 1:1000; fig 2
| Maldonado H, RamÃrez E, Utreras E, Pando M, Kettlun A, Chiong M, et al. Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes. J Neurosci Res. 2011;89:1489-98 pubmed publisher |
- western blot; human; 1:500; fig 2
| Haggerty T, Credle J, Rodriguez O, Wills J, Oaks A, Masliah E, et al. Hyperphosphorylated Tau in an ?-synuclein-overexpressing transgenic model of Parkinson's disease. Eur J Neurosci. 2011;33:1598-610 pubmed publisher |
- western blot; mouse; 1:500; fig 3
| Wills J, Credle J, Haggerty T, Lee J, Oaks A, Sidhu A. Tauopathic changes in the striatum of A53T ?-synuclein mutant mouse model of Parkinson's disease. PLoS ONE. 2011;6:e17953 pubmed publisher |
- immunohistochemistry - paraffin section; rat; 1:1000; fig 5
- western blot; rat; 1:2000; fig 4
| Nakajima T, Ochi S, Oda C, Ishii M, Ogawa K. Ischemic preconditioning attenuates of ischemia-induced degradation of spectrin and tau: implications for ischemic tolerance. Neurol Sci. 2011;32:229-39 pubmed publisher |
- western blot; human; 1:1000
| Spatara M, Robinson A. Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction. J Neurosci Res. 2010;88:1951-61 pubmed publisher |
| Hall E, Lee S, Mairuae N, Simmons Z, Connor J. Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues. Neurobiol Aging. 2011;32:1409-19 pubmed publisher |
- western blot; rat; 1:1000; fig 3
| Kim H, Sul D, Lim J, Lee D, Joo S, Hwang K, et al. Delphinidin ameliorates beta-amyloid-induced neurotoxicity by inhibiting calcium influx and tau hyperphosphorylation. Biosci Biotechnol Biochem. 2009;73:1685-9 pubmed |
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| Sul D, Kim H, Lee D, Joo S, Hwang K, Park S. Protective effect of caffeic acid against beta-amyloid-induced neurotoxicity by the inhibition of calcium influx and tau phosphorylation. Life Sci. 2009;84:257-62 pubmed publisher |
- western blot; mouse; 1:1000
| Sul D, Kim H, Cho E, Lee M, Kim H, Jung W, et al. 2,3,7,8-TCDD neurotoxicity in neuroblastoma cells is caused by increased oxidative stress, intracellular calcium levels, and tau phosphorylation. Toxicology. 2009;255:65-71 pubmed publisher |
- western blot; rat; 1:1000; fig 6
| Park S, Kim H, Cho E, Kwon B, Phark S, Hwang K, et al. Curcumin protected PC12 cells against beta-amyloid-induced toxicity through the inhibition of oxidative damage and tau hyperphosphorylation. Food Chem Toxicol. 2008;46:2881-7 pubmed publisher |
- western blot; mouse; 1:1000; fig 3
| Fukuzaki E, Takuma K, Himeno Y, Yoshida S, Funatsu Y, Kitahara Y, et al. Enhanced activity of hippocampal BACE1 in a mouse model of postmenopausal memory deficits. Neurosci Lett. 2008;433:141-5 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Liu R, Zhou X, Tanila H, Bjorkdahl C, Wang J, Guan Z, et al. Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology. J Cell Mol Med. 2008;12:241-57 pubmed publisher |
- western blot; rat; 1:5000
| Selenica M, Jensen H, Larsen A, Pedersen M, Helboe L, Leist M, et al. Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylation. Br J Pharmacol. 2007;152:959-79 pubmed |
- immunohistochemistry - frozen section; human; 1:500
- western blot; human; 1:500
| Bai Q, Garver J, Hukriede N, Burton E. Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene. Nucleic Acids Res. 2007;35:6501-16 pubmed |
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| Jossin Y, Goffinet A. Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth. Mol Cell Biol. 2007;27:7113-24 pubmed |
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| Park S, Tournell C, Sinjoanu R, Ferreira A. Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons. Neuroscience. 2007;144:119-27 pubmed |
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- western blot; human; 1:10,000; tbl 1
| Schindowski K, Bretteville A, Leroy K, Bégard S, Brion J, Hamdane M, et al. Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. Am J Pathol. 2006;169:599-616 pubmed |
| Yoshida S, Maeda M, Kaku S, Ikeya H, Yamada K, Nakaike S. Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus. J Neural Transm (Vienna). 2006;113:1803-14 pubmed |
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| Lobsiger C, Garcia M, Ward C, Cleveland D. Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS. Proc Natl Acad Sci U S A. 2005;102:10351-6 pubmed |
| Kerokoski P, Suuronen T, Salminen A, Soininen H, Pirttila T. Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation. Biochem Biophys Res Commun. 2002;298:693-8 pubmed |
| Kubota H, Kunisawa K, Wulaer B, Hasegawa M, Kurahashi H, Sakata T, et al. High salt induces cognitive impairment via the interaction of the angiotensin II-AT1 and prostaglandin E2-EP1 systems. Br J Pharmacol. 2023;180:2393-2411 pubmed publisher |
| Riba M, del Valle J, Romera C, Alsina R, Molina Porcel L, Pelegr xed C, et al. Uncovering tau in wasteosomes (corpora amylacea) of Alzheimer's disease patients. Front Aging Neurosci. 2023;15:1110425 pubmed publisher |
| Car xfa s Cadavieco M, Berenguer L xf3 pez I, Montoro Canelo A, Serrano Lope M, Gonz xe1 lez de la Fuente S, Aguado B, et al. Cognitive decline in diabetic mice predisposed to Alzheimer's disease is greater than in wild type. Life Sci Alliance. 2023;6: pubmed publisher |
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| Korde D, Humpel C. Spreading of P301S Aggregated Tau Investigated in Organotypic Mouse Brain Slice Cultures. Biomolecules. 2022;12: pubmed publisher |
| Mai M, Guo X, Huang Y, Zhang W, Xu Y, Zhang Y, et al. DHCR24 Knockdown Induces Tau Hyperphosphorylation at Thr181, Ser199, Ser262, and Ser396 Sites via Activation of the Lipid Raft-Dependent Ras/MEK/ERK Signaling Pathway in C8D1A Astrocytes. Mol Neurobiol. 2022;59:5856-5873 pubmed publisher |
| Tabassum Z, Tseng J, Isemann C, Tian X, Chen Y, Herring L, et al. Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase. J Biol Chem. 2022;298:101977 pubmed publisher |
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| Choi M, Kim T, Ahn J, Lee J, Jung B, An S, et al. Conformation-specific Antibodies Targeting Aggregated Forms of α-synuclein Block the Propagation of Synucleinopathy. Exp Neurobiol. 2022;31:29-41 pubmed publisher |
| Almansa D, Peinado H, Garcia Rodriguez R, Casadomé Perales Á, Dotti C, Guix F. Extracellular Vesicles Derived from Young Neural Cultures Attenuate Astrocytic Reactivity In Vitro. Int J Mol Sci. 2022;23: pubmed publisher |
| Wang X, Qi L, Cheng Y, Ji X, Chi T, Liu P, et al. PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease. Acta Pharmacol Sin. 2022;43:1916-1927 pubmed publisher |
| Saroja S, Sharma A, Hof P, Pereira A. Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease. Alzheimers Dement. 2022;18:1602-1615 pubmed publisher |
| Lyons C, Zhou X, Razzoli M, Chen M, Xia W, Ashe K, et al. Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice. Eur J Neurosci. 2022;55:2971-2985 pubmed publisher |
| Caroux E, Redeker V, Madiona K, Melki R. Structural mapping techniques distinguish the surfaces of fibrillar 1N3R and 1N4R human tau. J Biol Chem. 2021;297:101252 pubmed publisher |
| Hashem J, Hu M, Zhang J, Gao F, Chen C. Inhibition of 2-Arachidonoylglycerol Metabolism Alleviates Neuropathology and Improves Cognitive Function in a Tau Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2021;58:4122-4133 pubmed publisher |
| Ye T, Duan Y, Tsang H, Xu H, Chen Y, Cao H, et al. Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases. Commun Biol. 2021;4:195 pubmed publisher |
| Zhao D, Zhou Y, Huo Y, Meng J, Xiao X, Han L, et al. RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation. Cell Death Differ. 2021;28:337-348 pubmed publisher |
| Krishnan V, Thanigaiarasu L, White R, Crew R, Larcher T, Le Guiner C, et al. Dystrophic Dmdmdx rats show early neuronal changes (increased S100β and Tau5) at 8 months, supporting severe dystropathology in this rodent model of Duchenne muscular dystrophy. Mol Cell Neurosci. 2020;108:103549 pubmed publisher |
| Mankhong S, Kim S, Moon S, Lee K, Jeon H, Hwang B, et al. Effects of Aerobic Exercise on Tau and Related Proteins in Rats with the Middle Cerebral Artery Occlusion. Int J Mol Sci. 2020;21: pubmed publisher |
| Briner A, Götz J, Polanco J. Fyn Kinase Controls Tau Aggregation In Vivo. Cell Rep. 2020;32:108045 pubmed publisher |
| Landa J, Gaig C, Plagum xe0 J, Saiz A, Antonell A, Sanchez Valle R, et al. Effects of IgLON5 Antibodies on Neuronal Cytoskeleton: A Link between Autoimmunity and Neurodegeneration. Ann Neurol. 2020;88:1023-1027 pubmed publisher |
| Adhikari R, Yang M, Saikia N, Dutta C, Alharbi W, Shan Z, et al. Acetylation of Aβ42 at Lysine 16 Disrupts Amyloid Formation. ACS Chem Neurosci. 2020;11:1178-1191 pubmed publisher |
| Tai C, Chang C, Yu G, Lopez I, Yu X, Wang X, et al. Tau Reduction Prevents Key Features of Autism in Mouse Models. Neuron. 2020;106:421-437.e11 pubmed publisher |
| Hou T, Zhou Y, Zhu L, Wang X, Pang P, Wang D, et al. Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease. J Neurochem. 2020;154:441-457 pubmed publisher |
| Lo C, Lim C, Ding Z, Wickramasinghe S, Braun A, Ashe K, et al. Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies. Alzheimers Dement. 2019;15:1489-1502 pubmed publisher |
| Martorell A, Paulson A, Suk H, Abdurrob F, Drummond G, Guan W, et al. Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell. 2019;177:256-271.e22 pubmed publisher |
| Meyer K, Feldman H, Lu T, Drake D, Lim E, Ling K, et al. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Rep. 2019;26:1112-1127.e9 pubmed publisher |
| Zheng Y, Liu A, Wang Z, Cao Q, Wang W, Lin L, et al. Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer's disease. Brain. 2019;142:787-807 pubmed publisher |
| Borin M, Saraceno C, Catania M, Lorenzetto E, Pontelli V, Paterlini A, et al. Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer's disease. Acta Neuropathol Commun. 2018;6:61 pubmed publisher |
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