Mouse IFN-gamma, Animal-Free Recombinant Protein, PeproTech | Invitrogen AF-315-05-250UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Mouse IFN-gamma, Animal-Free Recombinant Protein, PeproTech

catalog :

AF-315-05-250UG

quantity :

250 ug

price :

US 486.00

citations: 26

Reference
Wang M, Zhao M, Zheng Z, Pan W, Zhang J, Yin Z, et al. TRPA1 deficiency aggravates dilated cardiomyopathy by promoting S100A8 expression to induce M1 macrophage polarization in rats. FASEB J. 2023;37:e22982 pubmed publisher
Moreira J, Iakhiaev A, Vankayalapati R, Jung B, Samten B. Histone deacetylase-2 controls IL-1β production through the regulation of NLRP3 expression and activation in tuberculosis infection. iScience. 2022;25:104799 pubmed publisher
Tanyi J, Chiang C, Chiffelle J, Thierry A, Baumgartener P, Huber F, et al. Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer. NPJ Vaccines. 2021;6:36 pubmed publisher
Li S, Kuang M, Chen L, Li Y, Liu S, Du H, et al. The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling. Cell Rep. 2021;34:108631 pubmed publisher
Zhou H, Peng X, Hu J, Wang L, Luo H, Zhang J, et al. DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production. Nat Commun. 2021;12:326 pubmed publisher
Guo Q, Zhu X, Wei R, Zhao L, Zhang Z, Yin X, et al. miR-130b-3p regulates M1 macrophage polarization via targeting IRF1. J Cell Physiol. 2020;: pubmed publisher
Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, et al. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020;10:13751 pubmed publisher
Usui J, Yaguchi M, Yamazaki S, Takahashi Kobayashi M, Kawamura T, Kaneko S, et al. Transcription factor 21 expression in injured podocytes of glomerular diseases. Sci Rep. 2020;10:11516 pubmed publisher
Gajdasik D, Gaspal F, Halford E, Fiancette R, Dutton E, Willis C, et al. Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues. Nat Commun. 2020;11:3421 pubmed publisher
Overall S, Toor J, Hao S, Yarmarkovich M, Sara M O Rourke -, Morozov G, et al. High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange. Nat Commun. 2020;11:1909 pubmed publisher
Zhang K, Shi Z, Zhang M, Dong X, Zheng L, Li G, et al. Silencing lncRNA Lfar1 alleviates the classical activation and pyoptosis of macrophage in hepatic fibrosis. Cell Death Dis. 2020;11:132 pubmed publisher
Liu H, Zhu Y, Gao Y, Qi D, Zhao L, Zhao L, et al. NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis. Cell Death Dis. 2020;11:129 pubmed publisher
Huang K, Masuda A, Chen G, Bushra S, Kamon M, Araki T, et al. Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells. Sci Rep. 2020;10:2558 pubmed publisher
Souza Moreira L, Soares V, Dias S, Bozza P. Adipose-derived Mesenchymal Stromal Cells Modulate Lipid Metabolism and Lipid Droplet Biogenesis via AKT/mTOR -PPARγ Signalling in Macrophages. Sci Rep. 2019;9:20304 pubmed publisher
Schneider A, Wood H, Geden S, Greene C, Yates R, Masternak M, et al. Growth hormone-mediated reprogramming of macrophage transcriptome and effector functions. Sci Rep. 2019;9:19348 pubmed publisher
Wiede F, Lu K, Du X, Liang S, Hochheiser K, Dodd G, et al. PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours. EMBO J. 2020;39:e103637 pubmed publisher
Bittel M, Kremer A, St xfc rzl M, Wirtz S, Stolzer I, Neurath M, et al. Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure. Cell Death Dis. 2019;10:878 pubmed publisher
Personnic N, Striednig B, Lezan E, Manske C, Welin A, Schmidt A, et al. Quorum sensing modulates the formation of virulent Legionella persisters within infected cells. Nat Commun. 2019;10:5216 pubmed publisher
Sonner J, Keil M, Falk Paulsen M, Mishra N, Rehman A, Kramer M, et al. Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology. Nat Commun. 2019;10:4877 pubmed publisher
Zhou L, Mudianto T, Ma X, Riley R, Uppaluri R. Targeting EZH2 Enhances Antigen Presentation, Antitumor Immunity, and Circumvents Anti-PD-1 Resistance in Head and Neck Cancer. Clin Cancer Res. 2019;: pubmed publisher
Kirby L, Jin J, Cardona J, Smith M, Martin K, Wang J, et al. Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination. Nat Commun. 2019;10:3887 pubmed publisher
Stone A, Green R, Wilkins C, Hemann E, Gale M. RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection. Nat Commun. 2019;10:3649 pubmed publisher
Yahata T, Mizoguchi M, Kimura A, Orimo T, Toujima S, Kuninaka Y, et al. Programmed cell death ligand 1 disruption by clustered regularly interspaced short palindromic repeats/Cas9-genome editing promotes antitumor immunity and suppresses ovarian cancer progression. Cancer Sci. 2019;110:1279-1292 pubmed publisher
Filliol A, Farooq M, Piquet Pellorce C, Genet V, Dimanche Boitrel M, Vandenabeele P, et al. RIPK1 protects hepatocytes from death in Fas-induced hepatitis. Sci Rep. 2017;7:9205 pubmed publisher
Matsuda T, Murao N, Katano Y, Juliandi B, Kohyama J, Akira S, et al. TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus. Nat Commun. 2015;6:6514 pubmed publisher
Wu X, Lahiri A, Haines G, Flavell R, Abraham C. NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury. J Immunol. 2014;192:3409-18 pubmed publisher

product information

Product Type :

Protein

Product Name :

Mouse IFN-gamma, Animal-Free Recombinant Protein, PeproTech

Catalog # :

AF-315-05-250UG

Quantity :

250 ug

Price :

US 486.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Mouse

Applications :

Functional Assay: Assay-dependent

Species :

Mouse

Storage :

-20 C

Description :

IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; Interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g