Human CXCL12 (SDF-1a), Animal-Free Recombinant Protein, PeproTech | Invitrogen AF-300-28A-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human CXCL12 (SDF-1a), Animal-Free Recombinant Protein, PeproTech

catalog :

AF-300-28A-100UG

quantity :

100 ug

price :

US 794.00

citations: 27

Reference
Egea V, Kessenbrock K, Lawson D, Bartelt A, Weber C, Ries C. Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release. Cell Death Dis. 2021;12:516 pubmed publisher
Weston C, Shepherd E, Claridge L, Rantakari P, Curbishley S, Tomlinson J, et al. Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. J Clin Invest. 2015;125:501-20 pubmed publisher
Mahevas M, Patin P, Huetz F, Descatoire M, Cagnard N, Bole Feysot C, et al. B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells. J Clin Invest. 2013;123:432-42 pubmed publisher
Timár C, Lorincz A, Csépányi Kömi R, Vályi Nagy A, Nagy G, Buzas E, et al. Antibacterial effect of microvesicles released from human neutrophilic granulocytes. Blood. 2013;121:510-8 pubmed publisher
Baumann T, Affentranger S, Niggli V. Evidence for chemokine-mediated coalescence of preformed flotillin hetero-oligomers in human T-cells. J Biol Chem. 2012;287:39664-72 pubmed publisher
Liberman J, Sartelet H, Flahaut M, Mühlethaler Mottet A, Coulon A, Nyalendo C, et al. Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma. PLoS ONE. 2012;7:e43665 pubmed publisher
Zhang S, Han Z, Jing Y, Tao S, Li T, Wang H, et al. CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients. BMC Med. 2012;10:85 pubmed publisher
Sakamoto A, Kawashiri M, Ishibashi Ueda H, Sugamoto Y, Yoshimuta T, Higashikata T, et al. Expression and Function of Ephrin-B1 and Its Cognate Receptor EphB2 in Human Abdominal Aortic Aneurysm. Int J Vasc Med. 2012;2012:127149 pubmed publisher
Skavland J, Jørgensen K, Hadziavdic K, Hovland R, Jonassen I, Bruserud O, et al. Specific cellular signal-transduction responses to in vivo combination therapy with ATRA, valproic acid and theophylline in acute myeloid leukemia. Blood Cancer J. 2011;1:e4 pubmed publisher
Azcutia V, Stefanidakis M, Tsuboi N, Mayadas T, CROCE K, Fukuda D, et al. Endothelial CD47 promotes vascular endothelial-cadherin tyrosine phosphorylation and participates in T cell recruitment at sites of inflammation in vivo. J Immunol. 2012;189:2553-62 pubmed publisher
Shi J, Ge M, Lu S, Li X, Shao Y, Huang J, et al. Intrinsic impairment of CD4(+)CD25(+) regulatory T cells in acquired aplastic anemia. Blood. 2012;120:1624-32 pubmed publisher
Kayali A, Lopez A, Hao E, Hinton A, Hayek A, King C. The SDF-1?/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells. PLoS ONE. 2012;7:e38721 pubmed publisher
Will B, Zhou L, Vogler T, Ben Neriah S, Schinke C, Tamari R, et al. Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations. Blood. 2012;120:2076-86 pubmed publisher
Hoffmann F, Müller W, Schütz D, Penfold M, Wong Y, Schulz S, et al. Rapid uptake and degradation of CXCL12 depend on CXCR7 carboxyl-terminal serine/threonine residues. J Biol Chem. 2012;287:28362-77 pubmed publisher
Chenivesse C, Chang Y, Azzaoui I, Ait Yahia S, Morales O, Ple C, et al. Pulmonary CCL18 recruits human regulatory T cells. J Immunol. 2012;189:128-37 pubmed publisher
Wang S, Nan K, Wang Y, Wang W, Tian T. The balance between two isoforms of LEF-1 regulates colon carcinoma growth. BMC Gastroenterol. 2012;12:53 pubmed publisher
Freeley M, O Dowd F, Paul T, Kashanin D, Davies A, Kelleher D, et al. L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes. J Immunol. 2012;188:6357-70 pubmed publisher
Bruns I, Cadeddu R, Brueckmann I, Fröbel J, Geyh S, Büst S, et al. Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells. Blood. 2012;120:2620-30 pubmed
Cui Y, Johnson T, Baumbach A, Reeves B, Rogers C, Angelini G, et al. Stepwise optimization of the procedure for assessment of circulating progenitor cells in patients with myocardial infarction. PLoS ONE. 2012;7:e30389 pubmed publisher
O Callaghan K, Lee L, Nguyen N, Hsieh M, Kaneider N, Klein A, et al. Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia. Blood. 2012;119:1717-25 pubmed publisher
Yang D, Postnikov Y, Li Y, Tewary P, de la Rosa G, Wei F, et al. High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses. J Exp Med. 2012;209:157-71 pubmed publisher
Schaeuble K, Hauser M, Singer E, Groettrup M, Legler D. Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration. J Immunol. 2011;187:5645-52 pubmed publisher
Saini V, Marchese A, Tang W, Majetschak M. Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction. J Biol Chem. 2011;286:44145-52 pubmed publisher
Trachtenberg A, Pushkarsky T, Heine S, Constant S, Brichacek B, Bukrinsky M. The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis. BMC Res Notes. 2011;4:396 pubmed publisher
Munk R, Ghosh P, Ghosh M, Saito T, Xu M, Carter A, et al. Involvement of mTOR in CXCL12 mediated T cell signaling and migration. PLoS ONE. 2011;6:e24667 pubmed publisher
Nasser M, Qamri Z, Deol Y, Smith D, Shilo K, Zou X, et al. Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion. PLoS ONE. 2011;6:e23901 pubmed publisher
Hyduk S, Rullo J, Cano A, Xiao H, Chen M, Moser M, et al. Talin-1 and kindlin-3 regulate alpha4beta1 integrin-mediated adhesion stabilization, but not G protein-coupled receptor-induced affinity upregulation. J Immunol. 2011;187:4360-8 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human CXCL12 (SDF-1a), Animal-Free Recombinant Protein, PeproTech

Catalog # :

AF-300-28A-100UG

Quantity :

100 ug

Price :

US 794.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Functional Assay: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1a; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1a; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1