Mouse IL-2, Animal-Free Recombinant Protein, PeproTech | Invitrogen AF-212-12-5UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Mouse IL-2, Animal-Free Recombinant Protein, PeproTech

catalog :

AF-212-12-5UG

quantity :

5 ug

price :

US 114.00

citations: 12

Reference
Fiancette R, Finlay C, Willis C, Bevington S, Soley J, Ng S, et al. Reciprocal transcription factor networks govern tissue-resident ILC3 subset function and identity. Nat Immunol. 2021;22:1245-1255 pubmed publisher
Cardoso F, Klein Wolterink R, Godinho Silva C, Domingues R, Ribeiro H, da Silva J, et al. Neuro-mesenchymal units control ILC2 and obesity via a brain-adipose circuit. Nature. 2021;597:410-414 pubmed publisher
Cui J, Xu H, Yu J, Li Y, Chen Z, Zou Y, et al. IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation. Cell Death Dis. 2021;12:501 pubmed publisher
Tanyi J, Chiang C, Chiffelle J, Thierry A, Baumgartener P, Huber F, et al. Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer. NPJ Vaccines. 2021;6:36 pubmed publisher
Sapra L, Dar H, Bhardwaj A, Pandey A, Kumari S, Azam Z, et al. Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice. Sci Rep. 2021;11:1807 pubmed publisher
Dagher R, Copenhaver A, Besnard V, Berlin A, Hamidi F, Maret M, et al. IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration. Nat Commun. 2020;11:4786 pubmed publisher
Yang R, Huang H, Cui S, Zhou Y, Zhang T, Zhou Y. IFN-γ promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b. Cell Death Dis. 2020;11:603 pubmed publisher
Petrova T, Pesic J, Pardali K, Gaestel M, Arthur J. p38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells. Sci Rep. 2020;10:3479 pubmed publisher
Parisi G, Saco J, Salazar F, Tsoi J, Krystofinski P, Puig Saus C, et al. Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist. Nat Commun. 2020;11:660 pubmed publisher
Yang W, Chen X, Hu H. CD4+ T-Cell Differentiation In Vitro. Methods Mol Biol. 2020;2111:91-99 pubmed publisher
Kim B, Kim B, Kook Y, Kim B. Potential of recombinant Mycobacterium paragordonae expressing HIV-1 Gag as a prime vaccine for HIV-1 infection. Sci Rep. 2019;9:15515 pubmed publisher
Delconte R, Shi W, Sathe P, Ushiki T, Seillet C, Minnich M, et al. The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15. Immunity. 2016;44:103-115 pubmed publisher

product information

Product Type :

Protein

Product Name :

Mouse IL-2, Animal-Free Recombinant Protein, PeproTech

Catalog # :

AF-212-12-5UG

Quantity :

5 ug

Price :

US 114.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Mouse

Applications :

Functional Assay: Assay-dependent

Species :

Mouse

Storage :

-20 C

Description :

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF