This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human IL-3, Animal-Free Recombinant Protein, PeproTech
catalog :
AF-200-03-100UG
quantity :
100 ug
price :
US 794.00
citations: 45
Reference
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Rio P, Navarro S, Guenechea G, Sánchez Domínguez R, Lamana M, Yañez R, et al. Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients. Blood. 2017;130:1535-1542 pubmed publisher
Morris E, Fox T, Chakraverty R, Tendeiro R, Snell K, Rivat C, et al. Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult. Blood. 2017;130:1327-1335 pubmed publisher
Kapp K, Schneider J, Schneider L, Gollinge N, J xe4 nsch S, Schroff M, et al. Distinct immunological activation profiles of dSLIM® and ProMune® depend on their different structural context. Immun Inflamm Dis. 2016;4:446-462 pubmed
Wen W, Zhang J, Xu J, Su R, Neises A, Ji G, et al. Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors. Stem Cell Reports. 2016;6:873-884 pubmed publisher
Churko J, Burridge P, Wu J. Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative Sendai virus in chemically defined conditions. Methods Mol Biol. 2013;1036:81-8 pubmed publisher
Szabo A, Gogolak P, Pazmandi K, Kis Toth K, Riedl K, Wizel B, et al. The two-component adjuvant IC31® boosts type i interferon production of human monocyte-derived dendritic cells via ligation of endosomal TLRs. PLoS ONE. 2013;8:e55264 pubmed publisher
Klco J, Spencer D, Lamprecht T, Sarkaria S, Wylie T, Magrini V, et al. Genomic impact of transient low-dose decitabine treatment on primary AML cells. Blood. 2013;121:1633-43 pubmed publisher
Nakajima Takagi Y, Osawa M, Oshima M, Takagi H, Miyagi S, Endoh M, et al. Role of SOX17 in hematopoietic development from human embryonic stem cells. Blood. 2013;121:447-58 pubmed publisher
Yamagata Y, Parietti V, Stockholm D, Corre G, Poinsignon C, Touleimat N, et al. Lentiviral transduction of CD34(+) cells induces genome-wide epigenetic modifications. PLoS ONE. 2012;7:e48943 pubmed publisher
Li X, Ha C, Fu D, Xiao M. Micro-RNA30c negatively regulates REDD1 expression in human hematopoietic and osteoblast cells after gamma-irradiation. PLoS ONE. 2012;7:e48700 pubmed publisher
Mizrahi K, Stein J, Yaniv I, Kaplan O, Askenasy N. TNF-? has tropic rather than apoptotic activity in human hematopoietic progenitors: involvement of TNF receptor-1 and caspase-8. Stem Cells. 2013;31:156-66 pubmed publisher
Roy A, Cowan G, Mead A, Filippi S, Bohn G, Chaidos A, et al. Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21. Proc Natl Acad Sci U S A. 2012;109:17579-84 pubmed publisher
Thiollier C, Lopez C, Gerby B, Ignacimouttou C, Poglio S, Duffourd Y, et al. Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models. J Exp Med. 2012;209:2017-31 pubmed publisher
Shi B, Ren G, Hu Y, Wang S, Zhang Z, Yuan Z. HBsAg inhibits IFN-? production in plasmacytoid dendritic cells through TNF-? and IL-10 induction in monocytes. PLoS ONE. 2012;7:e44900 pubmed
Yang T, Jian W, Luo Y, Fu X, NOGUCHI C, Bungert J, et al. Acetylation of histone deacetylase 1 regulates NuRD corepressor complex activity. J Biol Chem. 2012;287:40279-91 pubmed publisher
Vatolin S, Khan S, Reu F. Direct chromatin PCR (DC-PCR): hypotonic conditions allow differentiation of chromatin states during thermal cycling. PLoS ONE. 2012;7:e44690 pubmed publisher
Williams A, Li L, Nguyen B, Brown P, Levis M, Small D. Fluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia. Blood. 2012;120:3069-79 pubmed publisher
Gori J, Chandrasekaran D, Kowalski J, Adair J, Beard B, D Souza S, et al. Efficient generation, purification, and expansion of CD34(+) hematopoietic progenitor cells from nonhuman primate-induced pluripotent stem cells. Blood. 2012;120:e35-44 pubmed
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Gao H, Wu X, Sun Y, Zhou S, Silberstein L, Zhu Z. Suppression of homeobox transcription factor VentX promotes expansion of human hematopoietic stem/multipotent progenitor cells. J Biol Chem. 2012;287:29979-87 pubmed publisher
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product information
Product Type :
Protein
Product Name :
Human IL-3, Animal-Free Recombinant Protein, PeproTech
Catalog # :
AF-200-03-100UG
Quantity :
100 ug
Price :
US 794.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Functional Assay: Assay-dependent
Species :
Human
Storage :
-20 C
Description :
Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Format :
Lyophilized
Applications w/Dilutions :
Functional Assay: Assay-dependent
Aliases :
BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA