This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human/Mouse/Rat Activin A, Animal-Free Recombinant Protein, PeproTech
catalog :
AF-120-14E-01M
quantity :
2 x 500 ug
price :
US 5000.00
citations: 33
Reference
Tshilenge K, Aguirre C, Bons J, Gerencser A, Basisty N, Song S, et al. Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets. Mol Cell Proteomics. 2023;22:100534 pubmed publisher
Ren Y, Zhang S, Liang Y, Gong Z, Cui Y, Song W. Feeder cells treated with ethanol can be used to maintain self-renewal and pluripotency of human pluripotent stem cells. FEBS Open Bio. 2023;13:279-292 pubmed publisher
Sugishita H, Kondo T, Ito S, Nakayama M, Yakushiji Kaminatsui N, Kawakami E, et al. Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes. Nat Commun. 2021;12:5341 pubmed publisher
Watanabe A, Tanaka A, Koga C, Matsumoto M, Okazaki Y, Kin T, et al. CD82 is a marker to isolate β cell precursors from human iPS cells and plays a role for the maturation of β cells. Sci Rep. 2021;11:9530 pubmed publisher
Truong V, Viken K, Geng Z, Barkan S, Johnson B, Ebeling M, et al. Automating Human Induced Pluripotent Stem Cell Culture and Differentiation of iPSC-Derived Retinal Pigment Epithelium for Personalized Drug Testing. SLAS Technol. 2021;26:287-299 pubmed publisher
He F, Li N, Huang H, Wang J, Yang X, Wang H, et al. LSD1 inhibition yields functional insulin-producing cells from human embryonic stem cells. Stem Cell Res Ther. 2020;11:163 pubmed publisher
Griffiths R, Woods S, Cheng A, Wang P, Griffiths Jones S, Ronshaugen M, et al. The Transcription Factor-microRNA Regulatory Network during hESC-chondrogenesis. Sci Rep. 2020;10:4744 pubmed publisher
Boon R, Kumar M, Tricot T, Elia I, Ordovas L, Jacobs F, et al. Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. Nat Commun. 2020;11:1393 pubmed publisher
Li J, Yang Y, Fan J, Xu H, Fan L, Li H, et al. Long noncoding RNA ANCR inhibits the differentiation of mesenchymal stem cells toward definitive endoderm by facilitating the association of PTBP1 with ID2. Cell Death Dis. 2019;10:492 pubmed publisher
Ye M, Ni Q, Qi H, Qian X, Chen J, Guo X, et al. Exosomes Derived from Human Induced Pluripotent Stem Cells-Endothelia Cells Promotes Postnatal Angiogenesis in Mice Bearing Ischemic Limbs. Int J Biol Sci. 2019;15:158-168 pubmed publisher
Southard S, Kotipatruni R, Rust W. Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents. PLoS ONE. 2018;13:e0203126 pubmed publisher
Lv L, Qi H, Guo X, Ni Q, Yan Z, Zhang L. Long Noncoding RNA uc001pwg.1 Is Downregulated in Neointima in Arteriovenous Fistulas and Mediates the Function of Endothelial Cells Derived from Pluripotent Stem Cells. Stem Cells Int. 2017;2017:4252974 pubmed publisher
Lee P, Truong B, Vega Crespo A, Gilmore W, Hermann K, Angarita S, et al. Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. Mol Ther Nucleic Acids. 2016;5:e394 pubmed publisher
Lichtmannegger J, Leitzinger C, Wimmer R, Schmitt S, Schulz S, Kabiri Y, et al. Methanobactin reverses acute liver failure in a rat model of Wilson disease. J Clin Invest. 2016;126:2721-35 pubmed publisher
Chan D, Azghadi S, Feng J, Lowry W. PTK7 marks the first human developmental EMT in vitro. PLoS ONE. 2012;7:e50432 pubmed publisher
Nakajima Takagi Y, Osawa M, Oshima M, Takagi H, Miyagi S, Endoh M, et al. Role of SOX17 in hematopoietic development from human embryonic stem cells. Blood. 2013;121:447-58 pubmed publisher
Rodr xed guez Mart xed nez G, Molina Hern xe1 ndez A, Velasco I. Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cells. PLoS ONE. 2012;7:e43797 pubmed publisher
Kajiwara M, Aoi T, Okita K, Takahashi R, Inoue H, Takayama N, et al. Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2012;109:12538-43 pubmed publisher
Mansour A, Gafni O, Weinberger L, Zviran A, Ayyash M, Rais Y, et al. The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming. Nature. 2012;488:409-13 pubmed publisher
Escribese M, Sierra Filardi E, Nieto C, Samaniego R, Sanchez Torres C, Matsuyama T, et al. The prolyl hydroxylase PHD3 identifies proinflammatory macrophages and its expression is regulated by activin A. J Immunol. 2012;189:1946-54 pubmed publisher
Umeda K, Zhao J, Simmons P, Stanley E, Elefanty A, Nakayama N. Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells. Sci Rep. 2012;2:455 pubmed publisher
Chang H, Liao Y, Chiang C, Chen Y, Lai Y, Chang Y, et al. Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc. Int J Mol Sci. 2012;13:3598-3617 pubmed publisher
Bar Y, Russ H, Sintov E, Anker Kitai L, Knoller S, Efrat S. Redifferentiation of expanded human pancreatic ?-cell-derived cells by inhibition of the NOTCH pathway. J Biol Chem. 2012;287:17269-80 pubmed publisher
Bourlier V, Sengen xe8 s C, Zakaroff Girard A, Decaunes P, Wdziekonski B, Galitzky J, et al. TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages. PLoS ONE. 2012;7:e31274 pubmed publisher
Ohmine S, Squillace K, Hartjes K, Deeds M, Armstrong A, Thatava T, et al. Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency. Aging (Albany NY). 2012;4:60-73 pubmed
Ber S, Lee C, Voiculescu O, Surani M. Dedifferentiation of foetal CNS stem cells to mesendoderm-like cells through an EMT process. PLoS ONE. 2012;7:e30759 pubmed publisher
Przybyla L, Voldman J. Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal. Proc Natl Acad Sci U S A. 2012;109:835-40 pubmed publisher
Xi Q, Wang Z, Zaromytidou A, Zhang X, Chow Tsang L, Liu J, et al. A poised chromatin platform for TGF-? access to master regulators. Cell. 2011;147:1511-24 pubmed publisher
Iacovino M, Bosnakovski D, Fey H, Rux D, Bajwa G, Mahen E, et al. Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells. Stem Cells. 2011;29:1580-8 pubmed
Russ H, Sintov E, Anker Kitai L, Friedman O, Lenz A, Toren G, et al. Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro. PLoS ONE. 2011;6:e25566 pubmed publisher
Liang Y, Yang B, Chen J, Lin Y, Huang C, Cheng Y, et al. Changes in glycosphingolipid composition during differentiation of human embryonic stem cells to ectodermal or endodermal lineages. Stem Cells. 2011;29:1995-2004 pubmed publisher
Hayashi K, Ohta H, Kurimoto K, Aramaki S, Saitou M. Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell. 2011;146:519-32 pubmed publisher
Song Z, Cai J, Liu Y, Zhao D, Yong J, Duo S, et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res. 2009;19:1233-42 pubmed publisher
product information
Product Type :
Protein
Product Name :
Human/Mouse/Rat Activin A, Animal-Free Recombinant Protein, PeproTech
Catalog # :
AF-120-14E-01M
Quantity :
2 x 500 ug
Price :
US 5000.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human, Mouse, Rat
Applications :
Functional Assay: Assay-dependent
Species :
Human, Mouse, Rat
Storage :
-20 C
Description :
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
Format :
Lyophilized
Applications w/Dilutions :
Functional Assay: Assay-dependent
Aliases :
activin A; activin beta-A chain; BMP7; BMP-7; Bone morphogenetic protein 7; EDF; Eptotermin alfa; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; INHB; Inhba; inhibin B subunit; inhibin beta A chain; inhibin beta A protein; inhibin beta A subunit; inhibin beta-A; inhibin beta-A-subunit; inhibin beta-subunit; inhibin subunit beta A; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1; OP1; OP-1; Osteogenic protein 1; unnamed protein product
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA