Human TGF-beta 3, Animal-Free Recombinant Protein, PeproTech | Invitrogen AF-100-36E-1MG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human TGF-beta 3, Animal-Free Recombinant Protein, PeproTech

catalog :

AF-100-36E-1MG

quantity :

1 mg

price :

US 6600.00

citations: 15

Reference
Harberts J, Siegmund M, Schnelle M, Zhang T, Lei Y, Yu L, et al. Robust neuronal differentiation of human iPSC-derived neural progenitor cells cultured on densely-spaced spiky silicon nanowire arrays. Sci Rep. 2021;11:18819 pubmed publisher
Li L, Conradson D, Bharat V, Kim M, Hsieh C, Minhas P, et al. A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation. Nat Metab. 2021;3:1242-1258 pubmed publisher
Saini C, Srivastava R, Tarique M, Kurra S, Khanna N, Ramesh V, et al. Elevated IL-6R on CD4+ T cells promotes IL-6 driven Th17 cell responses in patients with T1R leprosy reactions. Sci Rep. 2020;10:15143 pubmed publisher
Lee J, Shklovskaya E, Lim S, Carlino M, Menzies A, Stewart A, et al. Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition. Nat Commun. 2020;11:1897 pubmed publisher
Barter M, Bui C, Cheung K, Falk J, G xf3 mez R, Skelton A, et al. DNA hypomethylation during MSC chondrogenesis occurs predominantly at enhancer regions. Sci Rep. 2020;10:1169 pubmed publisher
Smits L, Reinhardt L, Reinhardt P, Glatza M, Monzel A, Stanslowsky N, et al. Modeling Parkinson's disease in midbrain-like organoids. NPJ Parkinsons Dis. 2019;5:5 pubmed publisher
Li M, Keenan C, Lopez Campos G, Mangum J, Chen Q, Prodanovic D, et al. A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases. iScience. 2019;12:232-246 pubmed publisher
Course M, Hsieh C, Tsai P, Codding Bui J, Shaltouki A, Wang X. Live Imaging Mitochondrial Transport in Neurons. Neuromethods. 2017;123:49-66 pubmed publisher
He H, Kuriyan A, Su C, Mahabole M, Zhang Y, Zhu Y, et al. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3. Sci Rep. 2017;7:43736 pubmed publisher
Chen X, Song F, Jhamb D, Li J, Bottino M, Palakal M, et al. The Axolotl Fibula as a Model for the Induction of Regeneration across Large Segment Defects in Long Bones of the Extremities. PLoS ONE. 2015;10:e0130819 pubmed publisher
Li G, Fox J, Liu Z, Liu J, Gao G, Jin Y, et al. Lyn mitigates mouse airway remodeling by downregulating the TGF-?3 isoform in house dust mite models. J Immunol. 2013;191:5359-70 pubmed publisher
Tang R, Gao M, Wu M, Liu H, Zhang X, Liu B. High glucose mediates endothelial-to-chondrocyte transition in human aortic endothelial cells. Cardiovasc Diabetol. 2012;11:113 pubmed publisher
Krawetz R, Wu Y, Martin L, Rattner J, Matyas J, Hart D. Synovial fluid progenitors expressing CD90+ from normal but not osteoarthritic joints undergo chondrogenic differentiation without micro-mass culture. PLoS ONE. 2012;7:e43616 pubmed publisher
Yoshida M, Okubo N, Chosa N, Hasegawa T, Ibi M, Kamo M, et al. TGF-?-operated growth inhibition and translineage commitment into smooth muscle cells of periodontal ligament-derived endothelial progenitor cells through Smad- and p38 MAPK-dependent signals. Int J Biol Sci. 2012;8:1062-74 pubmed publisher
Lee D, Yoon W, Cho E, Kim H, Gronostajski R, Cho M, et al. Crosstalk between nuclear factor I-C and transforming growth factor-?1 signaling regulates odontoblast differentiation and homeostasis. PLoS ONE. 2011;6:e29160 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human TGF-beta 3, Animal-Free Recombinant Protein, PeproTech

Catalog # :

AF-100-36E-1MG

Quantity :

1 mg

Price :

US 6600.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Functional Assay: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

Transforming growth factor beta 3 (TGF beta 3) is the third member of the transforming growth factor family of cytokines, which also includes TGF beta 1 and beta 2. These cytokines are secreted in precursor form consisting of a bioactive C-terminal domain attached to an N-terminal domain known as latency associated protein (LAP). Cleavage of LAP results in the mature protein, which functions as a disulfide-linked homodimer. As with all members of the family, TGF beta 3 is highly conserved across species, with mouse and human TGF beta 3 demonstrating 100% sequence homology and cross-species activity.The members of this family can be expressed by most cell types and exert pleiotropic effects, which include the suppression of B- and T-cell effector activity, mediation of tissue healing, and suppression of tumor proliferation. The promotion of CD4+CD25+ T-cell expansion is a newly discovered function of the TGF beta cytokines, and indicates an important role in the protection against autoimmunity.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

ARVD; ARVD1; FLJ16571; H-TGF-b-3; LAP; Latency-associated peptide; LDS5; prepro-transforming growth factor beta-3; RNHF; TGF beta 3; Tgfb3; TGF-B3; Tgfb-3; TGF-beta3; TGF-beta-3; Transforming growth factor; transforming growth factor beta 3; transforming growth factor beta precursor; transforming growth factor beta-3; Transforming growth factor beta-3 proprotein; transforming growth factor, beta 3; transforming growth factor-beta3